Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4253001..4254684 Replicon chromosome
Accession NZ_CP065748
Organism Delftia lacustris strain FDAARGOS_890

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag I6G47_RS19880 Protein ID WP_034348397.1
Coordinates 4253830..4254684 (-) Length 285 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A072T3J4
Locus tag I6G47_RS19875 Protein ID WP_016449819.1
Coordinates 4253001..4253807 (-) Length 269 a.a.

Genomic Context

I6G47_RS19850I6G47_RS19855I6G47_RS19860I6G47_RS19845I6G47_RS19865I6G47_RS19870I6G47_RS19875I6G47_RS19880I6G47_RS19885I6G47_RS19890I6G47_RS19895I6G47_RS19900I6G47_RS19905
Location: 4250080..4250355 (276 bp)
Type: Others
Protein ID: WP_016452048.1
Location: 4250619..4250966 (348 bp)
Type: Others
Protein ID: Protein_3917
Location: 4250963..4251271 (309 bp)
Type: Others
Protein ID: WP_016452050.1
Location: 4248655..4249425 (771 bp)
Type: Others
Protein ID: WP_012202888.1
Location: 4251284..4252045 (762 bp)
Type: Others
Protein ID: WP_016452051.1
Location: 4252149..4252946 (798 bp)
Type: Others
Protein ID: WP_016452052.1
Location: 4253001..4253807 (807 bp)
Type: Antitoxin
Protein ID: WP_016449819.1
Location: 4253830..4254684 (855 bp)
Type: Toxin
Protein ID: WP_034348397.1
Location: 4254834..4255364 (531 bp)
Type: Others
Protein ID: WP_016449821.1
Location: 4255564..4256760 (1197 bp)
Type: Others
Protein ID: WP_016452054.1
Location: 4256783..4257667 (885 bp)
Type: Others
Protein ID: WP_016452055.1
Location: 4257804..4258394 (591 bp)
Type: Others
Protein ID: WP_013804518.1
Location: 4258476..4258967 (492 bp)
Type: Others
Protein ID: WP_016449824.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6G47_RS198454248655..4249425-771WP_012202888.1SDR family oxidoreductase-
I6G47_RS198504250080..4250355+276WP_016452048.1hypothetical protein-
I6G47_RS198554250619..4250966+348Protein_3917type II toxin-antitoxin system RelE/ParE family toxin-
I6G47_RS198604250963..4251271+309WP_016452050.1XRE family transcriptional regulator-
I6G47_RS198654251284..4252045-762WP_016452051.15'-methylthioadenosine/adenosylhomocysteine nucleosidase-
I6G47_RS198704252149..4252946-798WP_016452052.1aspartate dehydrogenase-
I6G47_RS198754253001..4253807-807WP_016449819.1IclR family transcriptional regulatorAntitoxin
I6G47_RS198804253830..4254684-855WP_034348397.1alpha/beta fold hydrolaseToxin
I6G47_RS198854254834..4255364-531WP_016449821.1cupin domain-containing protein-
I6G47_RS198904255564..4256760-1197WP_016452054.1MFS transporter-
I6G47_RS198954256783..4257667-885WP_016452055.1NAD(P)-dependent oxidoreductase-
I6G47_RS199004257804..4258394-591WP_013804518.1TetR/AcrR family transcriptional regulator-
I6G47_RS199054258476..4258967-492WP_016449824.1Lrp/AsnC family transcriptional regulator-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(43-270)

Antitoxin

Transcription regulator IclR, C-terminal

(137-255)


Sequences

Toxin        


Download         Length: 285 a.a.        Molecular weight: 29506.90 Da        Isoelectric Point: 7.3739

>T183316 WP_034348397.1 NZ_CP065748:c4254684-4253830 [Delftia lacustris]
MTPSVTACMEQRLQAQFPEHLIALPGGAQVAWREAGDTASDFAVVMLHGISSGAASWMDVALALAPRTRVLAWDAPGYGR
STPLAPAAPTGADYARVLDQSLQVLGVRRCLLVGHSLGALMGTPWAVQAGAGRVQQLVLISPAGGYGAPGMGEQQAKVRQ
GRLAALQEKGIEGLAAAIDQRLVSPAAPEPVRQWVRWNTARLHAAGYAQAVELLCGSDLGQAAGRLAMPVEVWVGEHDVV
TPPAACAAWAARLGARYVTLAAAGHASVVEQPADVAQRLATLLT

Download         Length: 855 bp

>T183316 NZ_CP086886:3808623-3808886 [Pseudosulfitobacter pseudonitzschiae]
ATGAAGTTCGAGTATGACCCTGACAAGAGTGCCGGGAACAAGGCCAAGCACGGCATCGACTTCGATGAAGCGCAAGCGCT
TTGGGAAGACCCGTGGCTGTTGGAGGCTCCCGCTCGAACAGATGACGAGCCGCGCTTTTTTGCAATAGGCATGATCAAGG
AACGGCATTGGTCAGCAGTTTGCACCTATCGCGGTGATATTATTCGGATCATCTCGGTGCGCCGCGCCAGAAAACAGGAG
ATTGAGCACTATGAAAGCACGTGA

Antitoxin


Download         Length: 269 a.a.        Molecular weight: 29047.08 Da        Isoelectric Point: 5.3408

>AT183316 WP_016449819.1 NZ_CP065748:c4253807-4253001 [Delftia lacustris]
MSDTSETLSNDNDRYTVPALERGLRLLACFTPSQPVWSAPDLARTLALPRSTVFRMLTTLEGMGYLQRSGTEYRLGLAVL
RLGYDYLSTQPLAQLAEPVLQSLCDRLGFTTNLALLDGTSVVYVARIAPAGAFQGAVRVGSRLPAHATVLGRALLQDMDA
DQLRALFGGSELPQFSESTPRSVEQLLQLLQQDHERGYAMGEGFYEPGVSSIAAPVRDAQGRIVAGLGMAVAFTEIAPGR
MADWVEQVRAAADELAGHLRTQHPGFLR

Download         Length: 807 bp

>AT183316 NZ_CP086886:3808873-3809088 [Pseudosulfitobacter pseudonitzschiae]
ATGAAAGCACGTGAGTTCGATCAAAAATTTGACACAGGTGAGAACGTCAGCGATCTTGTGGACTGGTCCAAAGCTAGGCG
GACGAATACCCAGACGAAGCGAGTCAATGTGGATTTTCCGTCGTGGGTCGTTTCTGGTTTGGATCAGAAGGCAAAGCAGC
TCGGCGTTACTCGTCAGTCGCTCATCAAACTCTGGATCGCCGAGCGGCTCCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A072T3J4

References