Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 1426660..1427259 Replicon chromosome
Accession NZ_CP065720
Organism Pseudomonas stutzeri strain FDAARGOS_877

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag I6G34_RS06475 Protein ID WP_102839342.1
Coordinates 1426660..1426998 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID -
Locus tag I6G34_RS06480 Protein ID WP_102839343.1
Coordinates 1427011..1427259 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G34_RS06470 1422832..1426296 - 3465 WP_146030726.1 type I restriction-modification system endonuclease -
I6G34_RS06475 1426660..1426998 - 339 WP_102839342.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6G34_RS06480 1427011..1427259 - 249 WP_102839343.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
I6G34_RS06485 1427870..1428454 + 585 WP_102839674.1 hypothetical protein -
I6G34_RS06490 1428702..1428899 + 198 WP_102839344.1 hypothetical protein -
I6G34_RS06495 1429054..1429332 + 279 WP_102839345.1 hypothetical protein -
I6G34_RS06500 1429365..1429661 + 297 WP_102839346.1 hypothetical protein -
I6G34_RS06505 1429673..1429909 + 237 WP_102839347.1 hypothetical protein -
I6G34_RS06510 1430399..1431217 - 819 WP_102839348.1 hypothetical protein -
I6G34_RS06515 1431300..1431515 - 216 WP_146030721.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1409468..1471528 62060


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-96)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12717.38 Da        Isoelectric Point: 4.4536

>T183278 WP_102839342.1 NZ_CP065720:c1426998-1426660 [Pseudomonas stutzeri]
MTTFDVRFTDSASQSIEDQIHHLAVYQGTEAALAKVNSLVDVITDKLRSTPMGYPVSQQASELGIIQYRELNTDGYRVFY
EIYDSDIAVELVIRQKQSVEQALIRYCLLNPL

Download         Length: 339 bp

>T183278 NZ_CP086848:224889-225215 [Pseudosulfitobacter pseudonitzschiae]
GTGAGGCGTGGTGAGCTGGTGACGGTCGCCCTTCAGGGCGACCACGGCAAGCCGCGTCCCGCGCTTGTGATCCAATCCGA
CCGGTTTCCGGACACCGCCACCACGACCGTCCTTCTGGTTACATCCACCTTGGTGGATGCGCCGTTGATTCGGCTGACGG
TCGAACCCTCTGCGGAGAACGGGTTGCGTATGCGATCACAGATCATGATCGACAAAGCCGTGACAGTTCGAACGGACAAG
CTGGGGAAAGCTTTCGGTCAGCTGGACGATACCGCCATGATCGAGGTGAACCGGGCACTAGCACTGTTTTTAGGAGTGGC
GGGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9312.66 Da        Isoelectric Point: 8.9265

>AT183278 WP_102839343.1 NZ_CP065720:c1427259-1427011 [Pseudomonas stutzeri]
MRVETISYLKRHAADLDLDEPMVVTQNGVPAYVVESYADRKRRDEAIALVKLLAIGSREYAQGKHCSADELKARLARRFA
QH

Download         Length: 249 bp

>AT183278 NZ_CP086848:224674-224892 [Pseudosulfitobacter pseudonitzschiae]
ATGCCAACCTCTGTTTCTCACCGTGTCCAGAAGCGTCGCGATGCCTTGCGTGCCGCTGGTTTGCGCCCCGTCCAGATTTG
GGTGCCGGATACCCGCCGCCCCGGTTTCGAGGCTGAGTGCCGCCGCCAGGCTGCAATTGTAGCCAAGGCCGATCGCGCAG
ATGATACTCTGAACGATTTCCTGGATGCCTCCCTGGTCGATGTGGATGACTGGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References