Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2904397..2904953 Replicon chromosome
Accession NZ_CP065699
Organism Serratia plymuthica strain FDAARGOS_889

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag I6G46_RS13825 Protein ID WP_166728989.1
Coordinates 2904663..2904953 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6G46_RS13820 Protein ID WP_166728990.1
Coordinates 2904397..2904675 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G46_RS13795 2899738..2900577 - 840 WP_006323781.1 MurR/RpiR family transcriptional regulator -
I6G46_RS13800 2900722..2902308 + 1587 WP_197912128.1 gamma-glutamyltransferase -
I6G46_RS13805 2902333..2902524 + 192 WP_006322394.1 oxalurate catabolism protein HpxX -
I6G46_RS13810 2902521..2903921 + 1401 WP_197912129.1 AtzE family amidohydrolase -
I6G46_RS13815 2903925..2904311 + 387 WP_004949013.1 oxalurate catabolism protein HpxZ -
I6G46_RS13820 2904397..2904675 + 279 WP_166728990.1 CopG family ribbon-helix-helix protein Antitoxin
I6G46_RS13825 2904663..2904953 + 291 WP_166728989.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6G46_RS13830 2904963..2905847 - 885 WP_197912130.1 siderophore-interacting protein -
I6G46_RS13835 2905853..2907076 - 1224 WP_197912131.1 MFS transporter -
I6G46_RS13840 2907214..2908959 + 1746 WP_006323773.1 aerobactin synthase IucA -
I6G46_RS13845 2908956..2909906 + 951 WP_197912132.1 acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10932.70 Da        Isoelectric Point: 9.9087

>T183234 WP_166728989.1 NZ_CP065699:2904663-2904953 [Serratia plymuthica]
VPQLIWTPAALLDVQRLYRFLAEKDLNSAKRAVATIRNCIKIIAHQPHIGRPAKDMAPEFREWPIDFGNSGYLVLYRFNG
VTAVILAIRHQSETGY

Download         Length: 291 bp

>T183234 NZ_CP086805:43457-43732 [Pseudosulfitobacter pseudonitzschiae]
GTGCCTGACCTTGAATGGAAGGCATTGGCGGTCGCGGACCTGATGGCGATTGTTGACTATATCTCGGATGACAATCCCGA
TGCCGCAATTTCCCTGATGGATGACATTCAAGACAAGGTGCTTGGCCTTCTGACGCATCCCAAATCCGGCCGCCCCGGTA
GGGTGAACGACACGCGAGAGCTGGTGATCCGGCCCAACTATATCGTCGTCTATGCTGAAAACACGGCGGCGGTCACCATT
CTGCGCGTTCTTCATGCGGTGCAGATGTGGCCCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10627.68 Da        Isoelectric Point: 4.9323

>AT183234 WP_166728990.1 NZ_CP065699:2904397-2904675 [Serratia plymuthica]
MATATSIKIDDELKQRVQHIAAAHQRSAHWIMREAIREYVEREEKREAVRNDALQAWETYQANGKHLTQDEADGWLSDLE
KGDDTEIPGCHN

Download         Length: 279 bp

>AT183234 NZ_CP086805:43171-43464 [Pseudosulfitobacter pseudonitzschiae]
ATGTCCGCTCAAACCTCGATGATTCATGTTCGTGTAGATGATCAGCTCAAGGCAAAGGCCACGGATGCCCTGTCCGGTGT
CGGCCTGACGTTGTCGGACGCCGTGCGCATCCTGCTGACCCGCGTGGCAGCAGAGGGTGGCTTGCCCGCAGGGTTGACGG
CAAATCCTGACGCCTACGATGCCTGGTTCCGCGCCAAGGTACAGGACGCATTGGCCGACGCAGCACCGGCCAAGCCGCAC
GATCAGGTGATGCGAGACGCGCGCGCCTTGATCGACGGCAAGCGCGGTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References