Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 6009180..6009853 Replicon chromosome
Accession NZ_CP065695
Organism Delftia acidovorans strain FDAARGOS_891

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I6G48_RS27585 Protein ID WP_050771858.1
Coordinates 6009443..6009853 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I6G48_RS27580 Protein ID WP_012205584.1
Coordinates 6009180..6009446 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G48_RS27555 6004276..6005556 - 1281 WP_012205589.1 TRAP transporter large permease subunit -
I6G48_RS27560 6005569..6006075 - 507 WP_012205588.1 TRAP transporter small permease -
I6G48_RS27565 6006094..6006612 - 519 WP_043781962.1 gluconokinase -
I6G48_RS27570 6006901..6007932 + 1032 WP_043783527.1 LacI family DNA-binding transcriptional regulator -
I6G48_RS27575 6007969..6008940 - 972 WP_012205585.1 chemotaxis protein -
I6G48_RS27580 6009180..6009446 + 267 WP_012205584.1 DNA-binding protein Antitoxin
I6G48_RS27585 6009443..6009853 + 411 WP_050771858.1 type II toxin-antitoxin system VapC family toxin Toxin
I6G48_RS27590 6009887..6011935 - 2049 WP_012205582.1 acetyl-CoA carboxylase biotin carboxylase subunit -
I6G48_RS27595 6012147..6013679 - 1533 WP_012205581.1 acyl-CoA carboxylase subunit beta -
I6G48_RS27600 6013736..6014809 - 1074 WP_192812290.1 methylmalonyl Co-A mutase-associated GTPase MeaB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15189.48 Da        Isoelectric Point: 7.3849

>T183222 WP_050771858.1 NZ_CP065695:6009443-6009853 [Delftia acidovorans]
MMLYMLDTNAASEAIRGNPLFDARLQALAPGQWCVSAVTCSELRYGIARRPEAVRLARIVEAFLHITAILPWDARAANQH
GQLRAYLRAQGSPIGDFDEMIAAHALALDAILVTDNVRHFERISGLRIENWLRQGH

Download         Length: 411 bp

>T183222 NZ_CP086793:c84455-84060 [Pseudosulfitobacter pseudonitzschiae]
ATGAGCGTTGAGTTCGCGGACACGAATGTCGTTCTTTACCTGCTCGACGACGGCCCAAAGGCCGATCGCGCCGAGGTCAT
CCTGGGGCAGGGGCCCCGGATCAGCGTTCAGGTTCTAAACGAGTCACTGGTGAACTGCCGCCGCAAAGCTGGCCTCGGTT
GGGAGGAAGCAGCGGCCTTTCTCGAAGGCGTGCGCGCCTTGTGTCCCGTCGAAGATCTCACCGTGCAGACCCATGACGTC
GGCCGCGCTTTGGCGGAACGCTACGGCTTCTCGATCTACGACGCGATGATCGTGGCCAGCGCTTTGGTTGCGGGGTGTAC
CACGCTGTGGAGCGAGGACATGCAAGATGGCCTGCTGGTGGAAGGCCAGCTTCGCATCGTCAACCCCTTTGCATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10097.25 Da        Isoelectric Point: 4.6388

>AT183222 WP_012205584.1 NZ_CP065695:6009180-6009446 [Delftia acidovorans]
MPPVTAQLFATDGVQAVKLPAEFRFEDRAEVYIRRDENTGDVILSTIPRADWSEFMRLRHQLGHAAESALPVRQQGSEQR
DPFQGWEE

Download         Length: 267 bp

>AT183222 NZ_CP086793:c84672-84445 [Pseudosulfitobacter pseudonitzschiae]
ATGCAGGTCGCAAAATGGGGTAACTCGCTGGCCGTCCGTTTGCCCGCGGAGCTCGTCCGAGAGCTTGGTCTCAAGGAGGG
TGATCAGATCGACCTGGTCAAGGACGACGGTCGGGTCAGAGTCCGTCGCCTTGCTCGTGCGGATGAGGTACTTACCGGCC
TGCGCCGCTTCCGGGGCAAGTTGTCCGCAGCAGAACGTCTGAGCCGCGACGACGCACATGAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References