Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 2725958..2727705 | Replicon | chromosome |
Accession | NZ_CP065684 | ||
Organism | Burkholderia oklahomensis strain FDAARGOS_900 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | I6G57_RS30845 | Protein ID | WP_010108748.1 |
Coordinates | 2725958..2726854 (+) | Length | 299 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | I6G57_RS30850 | Protein ID | WP_010108749.1 |
Coordinates | 2726851..2727705 (+) | Length | 285 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6G57_RS30815 | 2721361..2722449 | - | 1089 | WP_010108741.1 | porin | - |
I6G57_RS30820 | 2722883..2723200 | + | 318 | WP_010108742.1 | non-heme iron oxygenase ferredoxin subunit | - |
I6G57_RS30825 | 2723202..2723513 | + | 312 | WP_010108743.1 | hypothetical protein | - |
I6G57_RS30830 | 2723548..2724615 | + | 1068 | WP_041282028.1 | aromatic ring-hydroxylating dioxygenase subunit alpha | - |
I6G57_RS30835 | 2724612..2725382 | + | 771 | WP_010118458.1 | SDR family oxidoreductase | - |
I6G57_RS30840 | 2725414..2725941 | + | 528 | WP_010108747.1 | cupin domain-containing protein | - |
I6G57_RS30845 | 2725958..2726854 | + | 897 | WP_010108748.1 | alpha/beta fold hydrolase | Toxin |
I6G57_RS30850 | 2726851..2727705 | + | 855 | WP_010108749.1 | IclR family transcriptional regulator | Antitoxin |
I6G57_RS30855 | 2727702..2728499 | + | 798 | WP_010108750.1 | SDR family oxidoreductase | - |
I6G57_RS30860 | 2728492..2730165 | + | 1674 | WP_041282030.1 | thiamine pyrophosphate-binding protein | - |
I6G57_RS30865 | 2730158..2730973 | + | 816 | WP_010108754.1 | aspartate dehydrogenase | - |
I6G57_RS30870 | 2731005..2732495 | + | 1491 | WP_010108755.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 299 a.a. Molecular weight: 30711.76 Da Isoelectric Point: 7.3485
>T183174 WP_010108748.1 NZ_CP065684:2725958-2726854 [Burkholderia oklahomensis]
MSAISVTTNDIGATPFAELLERFPERRAAAGAAGAIGYREAGDARGERCPVVLLHGIGSGAASWVRQLDTLGATRRALAW
DAPGYGASSRVAAESPVAADYAASLDAWLDALRIERCVLVGHSLGAIVAGAFARAAGERLSGLLLISPAGGYGSAPADVR
AERRDSRLALLASLGPQGLAEQRSANMLSAHASDAARAWVRWNMARIVPAGYAQATHLLANADLATDLVHYRGRVAVAVG
ADDAITPPAACERIAQAARVGLQVIPRAGHAGYVEAPDAYGALIDAFCRQCDGLRGAA
MSAISVTTNDIGATPFAELLERFPERRAAAGAAGAIGYREAGDARGERCPVVLLHGIGSGAASWVRQLDTLGATRRALAW
DAPGYGASSRVAAESPVAADYAASLDAWLDALRIERCVLVGHSLGAIVAGAFARAAGERLSGLLLISPAGGYGSAPADVR
AERRDSRLALLASLGPQGLAEQRSANMLSAHASDAARAWVRWNMARIVPAGYAQATHLLANADLATDLVHYRGRVAVAVG
ADDAITPPAACERIAQAARVGLQVIPRAGHAGYVEAPDAYGALIDAFCRQCDGLRGAA
Download Length: 897 bp
>T183174 NZ_CP086728:c1386166-1385984 [Streptococcus parasuis]
ATGCCTATGACACAAAAAGAAATGGTTAAGCTACTTACCGCCCATGGTTGGACAAAAACCAAAGGAGGTAAGGGGTCACA
CGTGAAACTTGAAAAAGCAGGCGAGCGACCCATAACCATTCCCCACGGTGAAATAAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA
ATGCCTATGACACAAAAAGAAATGGTTAAGCTACTTACCGCCCATGGTTGGACAAAAACCAAAGGAGGTAAGGGGTCACA
CGTGAAACTTGAAAAAGCAGGCGAGCGACCCATAACCATTCCCCACGGTGAAATAAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA
Antitoxin
Download Length: 285 a.a. Molecular weight: 30991.45 Da Isoelectric Point: 6.6554
>AT183174 WP_010108749.1 NZ_CP065684:2726851-2727705 [Burkholderia oklahomensis]
MSEPLLKDADDAKNDSNYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYRL
GVAVLRLGFEYLSSLELTDLGLPVIEGLRDATGFTTHIVIRDGRDVVFVAKAQNAGHAFGSVRVNVGTRLPAHATTHGHV
LMGDLSLAQLCALYPEPALERVTKATPETVDALFSVIRDDARRGYGIGNSAFERDISVVTAPVRNDASKIVAVVTVTVPR
PEIDASLVADGLIDKVLRAAAELSRRLNYRPDDENTYLKALGLR
MSEPLLKDADDAKNDSNYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYRL
GVAVLRLGFEYLSSLELTDLGLPVIEGLRDATGFTTHIVIRDGRDVVFVAKAQNAGHAFGSVRVNVGTRLPAHATTHGHV
LMGDLSLAQLCALYPEPALERVTKATPETVDALFSVIRDDARRGYGIGNSAFERDISVVTAPVRNDASKIVAVVTVTVPR
PEIDASLVADGLIDKVLRAAAELSRRLNYRPDDENTYLKALGLR
Download Length: 855 bp
>AT183174 NZ_CP086728:c1385946-1385497 [Streptococcus parasuis]
ATGCTTGTCACTTATCCAGCTTTATTTTATTTTGATGATACAGACGGAGCTAACGCGCCCTACTTTGTAACATTCCCTGA
TTTTGAGCATTCAGCAACTCAAGGCGAGGATATGGCGGACGCTATGGCAATGGCTAGCGATTGGTTAGGCATGAACTTAG
CTGATTATATCGAGAATGGACGAGACATTCCTACCCCGTCTTCTATAAATACTTTGTCATTAGTAGATAATAACCCTTTC
CGTGATGAGGATTTTGAGATGGTTTACGATTCTAGCAAGTCTTTTATCTCCATGGTGATGGTGGATGTTGCAAAGTATTT
GGGCAGTCAAGAGCCAGTAAAGAAAACACTCACTATCCCACGCTGGGCAGACACTCTAGGACGTGAACTAGGATTGAATT
TCTCACAGACCCTCACGGATGCAATTGCAGATAAAAAGATCCATGCTTAA
ATGCTTGTCACTTATCCAGCTTTATTTTATTTTGATGATACAGACGGAGCTAACGCGCCCTACTTTGTAACATTCCCTGA
TTTTGAGCATTCAGCAACTCAAGGCGAGGATATGGCGGACGCTATGGCAATGGCTAGCGATTGGTTAGGCATGAACTTAG
CTGATTATATCGAGAATGGACGAGACATTCCTACCCCGTCTTCTATAAATACTTTGTCATTAGTAGATAATAACCCTTTC
CGTGATGAGGATTTTGAGATGGTTTACGATTCTAGCAAGTCTTTTATCTCCATGGTGATGGTGGATGTTGCAAAGTATTT
GGGCAGTCAAGAGCCAGTAAAGAAAACACTCACTATCCCACGCTGGGCAGACACTCTAGGACGTGAACTAGGATTGAATT
TCTCACAGACCCTCACGGATGCAATTGCAGATAAAAAGATCCATGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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