Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 2725958..2727705 Replicon chromosome
Accession NZ_CP065684
Organism Burkholderia oklahomensis strain FDAARGOS_900

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag I6G57_RS30845 Protein ID WP_010108748.1
Coordinates 2725958..2726854 (+) Length 299 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag I6G57_RS30850 Protein ID WP_010108749.1
Coordinates 2726851..2727705 (+) Length 285 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G57_RS30815 2721361..2722449 - 1089 WP_010108741.1 porin -
I6G57_RS30820 2722883..2723200 + 318 WP_010108742.1 non-heme iron oxygenase ferredoxin subunit -
I6G57_RS30825 2723202..2723513 + 312 WP_010108743.1 hypothetical protein -
I6G57_RS30830 2723548..2724615 + 1068 WP_041282028.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
I6G57_RS30835 2724612..2725382 + 771 WP_010118458.1 SDR family oxidoreductase -
I6G57_RS30840 2725414..2725941 + 528 WP_010108747.1 cupin domain-containing protein -
I6G57_RS30845 2725958..2726854 + 897 WP_010108748.1 alpha/beta fold hydrolase Toxin
I6G57_RS30850 2726851..2727705 + 855 WP_010108749.1 IclR family transcriptional regulator Antitoxin
I6G57_RS30855 2727702..2728499 + 798 WP_010108750.1 SDR family oxidoreductase -
I6G57_RS30860 2728492..2730165 + 1674 WP_041282030.1 thiamine pyrophosphate-binding protein -
I6G57_RS30865 2730158..2730973 + 816 WP_010108754.1 aspartate dehydrogenase -
I6G57_RS30870 2731005..2732495 + 1491 WP_010108755.1 aldehyde dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(51-280)

Antitoxin

(23-71)


Sequences


Toxin        


Download         Length: 299 a.a.        Molecular weight: 30711.76 Da        Isoelectric Point: 7.3485

>T183174 WP_010108748.1 NZ_CP065684:2725958-2726854 [Burkholderia oklahomensis]
MSAISVTTNDIGATPFAELLERFPERRAAAGAAGAIGYREAGDARGERCPVVLLHGIGSGAASWVRQLDTLGATRRALAW
DAPGYGASSRVAAESPVAADYAASLDAWLDALRIERCVLVGHSLGAIVAGAFARAAGERLSGLLLISPAGGYGSAPADVR
AERRDSRLALLASLGPQGLAEQRSANMLSAHASDAARAWVRWNMARIVPAGYAQATHLLANADLATDLVHYRGRVAVAVG
ADDAITPPAACERIAQAARVGLQVIPRAGHAGYVEAPDAYGALIDAFCRQCDGLRGAA

Download         Length: 897 bp

>T183174 NZ_CP086728:c1386166-1385984 [Streptococcus parasuis]
ATGCCTATGACACAAAAAGAAATGGTTAAGCTACTTACCGCCCATGGTTGGACAAAAACCAAAGGAGGTAAGGGGTCACA
CGTGAAACTTGAAAAAGCAGGCGAGCGACCCATAACCATTCCCCACGGTGAAATAAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA

Antitoxin


Download         Length: 285 a.a.        Molecular weight: 30991.45 Da        Isoelectric Point: 6.6554

>AT183174 WP_010108749.1 NZ_CP065684:2726851-2727705 [Burkholderia oklahomensis]
MSEPLLKDADDAKNDSNYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNYRL
GVAVLRLGFEYLSSLELTDLGLPVIEGLRDATGFTTHIVIRDGRDVVFVAKAQNAGHAFGSVRVNVGTRLPAHATTHGHV
LMGDLSLAQLCALYPEPALERVTKATPETVDALFSVIRDDARRGYGIGNSAFERDISVVTAPVRNDASKIVAVVTVTVPR
PEIDASLVADGLIDKVLRAAAELSRRLNYRPDDENTYLKALGLR

Download         Length: 855 bp

>AT183174 NZ_CP086728:c1385946-1385497 [Streptococcus parasuis]
ATGCTTGTCACTTATCCAGCTTTATTTTATTTTGATGATACAGACGGAGCTAACGCGCCCTACTTTGTAACATTCCCTGA
TTTTGAGCATTCAGCAACTCAAGGCGAGGATATGGCGGACGCTATGGCAATGGCTAGCGATTGGTTAGGCATGAACTTAG
CTGATTATATCGAGAATGGACGAGACATTCCTACCCCGTCTTCTATAAATACTTTGTCATTAGTAGATAATAACCCTTTC
CGTGATGAGGATTTTGAGATGGTTTACGATTCTAGCAAGTCTTTTATCTCCATGGTGATGGTGGATGTTGCAAAGTATTT
GGGCAGTCAAGAGCCAGTAAAGAAAACACTCACTATCCCACGCTGGGCAGACACTCTAGGACGTGAACTAGGATTGAATT
TCTCACAGACCCTCACGGATGCAATTGCAGATAAAAAGATCCATGCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References