Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 4886894..4887519 | Replicon | chromosome |
| Accession | NZ_CP065673 | ||
| Organism | Serratia plymuthica strain FDAARGOS_907 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | I6G64_RS22860 | Protein ID | WP_063201925.1 |
| Coordinates | 4887337..4887519 (-) | Length | 61 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | I6G64_RS22855 | Protein ID | WP_063201920.1 |
| Coordinates | 4886894..4887307 (-) | Length | 138 a.a. |
Genomic Context
Location: 4882123..4882845 (723 bp)
Type: Others
Protein ID: WP_004945948.1
Type: Others
Protein ID: WP_004945948.1
Location: 4882902..4883411 (510 bp)
Type: Others
Protein ID: WP_063201911.1
Type: Others
Protein ID: WP_063201911.1
Location: 4883537..4884529 (993 bp)
Type: Others
Protein ID: WP_063201914.1
Type: Others
Protein ID: WP_063201914.1
Location: 4884644..4885444 (801 bp)
Type: Others
Protein ID: WP_063201917.1
Type: Others
Protein ID: WP_063201917.1
Location: 4885444..4886106 (663 bp)
Type: Others
Protein ID: WP_006321381.1
Type: Others
Protein ID: WP_006321381.1
Location: 4886110..4886862 (753 bp)
Type: Others
Protein ID: WP_062871168.1
Type: Others
Protein ID: WP_062871168.1
Location: 4886894..4887307 (414 bp)
Type: Antitoxin
Protein ID: WP_063201920.1
Type: Antitoxin
Protein ID: WP_063201920.1
Location: 4887337..4887519 (183 bp)
Type: Toxin
Protein ID: WP_063201925.1
Type: Toxin
Protein ID: WP_063201925.1
Location: 4887686..4891654 (3969 bp)
Type: Others
Protein ID: WP_063201928.1
Type: Others
Protein ID: WP_063201928.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6G64_RS22825 | 4882123..4882845 | + | 723 | WP_004945948.1 | RNA polymerase sigma factor FliA | - |
| I6G64_RS22830 | 4882902..4883411 | + | 510 | WP_063201911.1 | flagella biosynthesis regulatory protein FliZ | - |
| I6G64_RS22835 | 4883537..4884529 | + | 993 | WP_063201914.1 | D-cysteine desulfhydrase | - |
| I6G64_RS22840 | 4884644..4885444 | + | 801 | WP_063201917.1 | cystine ABC transporter substrate-binding protein | - |
| I6G64_RS22845 | 4885444..4886106 | + | 663 | WP_006321381.1 | cystine ABC transporter permease | - |
| I6G64_RS22850 | 4886110..4886862 | + | 753 | WP_062871168.1 | L-cystine ABC transporter ATP-binding protein YecC | - |
| I6G64_RS22855 | 4886894..4887307 | - | 414 | WP_063201920.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| I6G64_RS22860 | 4887337..4887519 | - | 183 | WP_063201925.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| I6G64_RS22865 | 4887686..4891654 | - | 3969 | WP_063201928.1 | trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 61 a.a. Molecular weight: 6893.14 Da Isoelectric Point: 11.0382
>T183167 WP_063201925.1 NZ_CP065673:c4887519-4887337 [Serratia plymuthica]
VKSSELIRLLEREGWVLERIKGSHHQFKHPGSRLVITVPHPRKDLKPGTLRQIMKDAGLC
VKSSELIRLLEREGWVLERIKGSHHQFKHPGSRLVITVPHPRKDLKPGTLRQIMKDAGLC
Download Length: 183 bp
>T183167 NZ_CP086726:1822717-1822818 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
Antitoxin
Download Length: 138 a.a. Molecular weight: 15092.85 Da Isoelectric Point: 4.6961
>AT183167 WP_063201920.1 NZ_CP065673:c4887307-4886894 [Serratia plymuthica]
MFYPAYVHSDLDGSASGFFPDVPGCYFAGDTLDKAFEDAKGALDAHFELLSEDNQAIPRPQAVSFHLAQENDTLNGGQWL
LVDINMDKFDGRAERINITLPHRLLNRIDSLVQQHPGYGSRSAFLAAAARNELLKVG
MFYPAYVHSDLDGSASGFFPDVPGCYFAGDTLDKAFEDAKGALDAHFELLSEDNQAIPRPQAVSFHLAQENDTLNGGQWL
LVDINMDKFDGRAERINITLPHRLLNRIDSLVQQHPGYGSRSAFLAAAARNELLKVG
Download Length: 414 bp
>AT183167 NZ_CP086726:c1822940-1822763 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA