183166

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4072427..4072894 Replicon chromosome
Accession NZ_CP065673
Organism Serratia plymuthica strain FDAARGOS_907

Toxin (Protein)


Gene name relE Uniprot ID A0A1B1KUP0
Locus tag I6G64_RS19030 Protein ID WP_006316908.1
Coordinates 4072625..4072894 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U3Z4H1
Locus tag I6G64_RS19025 Protein ID WP_013814083.1
Coordinates 4072427..4072621 (+) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G64_RS19005 4070611..4070976 + 366 WP_063203195.1 DUF596 domain-containing protein -
I6G64_RS19010 4071097..4071312 + 216 WP_183044542.1 DUF637 domain-containing protein -
I6G64_RS19015 4071302..4071652 + 351 WP_063197303.1 DUF596 domain-containing protein -
I6G64_RS19020 4071729..4072280 - 552 WP_004951898.1 spermidine N1-acetyltransferase -
I6G64_RS19025 4072427..4072621 + 195 WP_013814083.1 hypothetical protein Antitoxin
I6G64_RS19030 4072625..4072894 + 270 WP_006316908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6G64_RS19035 4072948..4073586 - 639 WP_037433480.1 phosphoribosylglycinamide formyltransferase -
I6G64_RS19040 4073586..4074623 - 1038 WP_006316901.1 phosphoribosylformylglycinamidine cyclo-ligase -
I6G64_RS19045 4074879..4075505 + 627 WP_006327216.1 uracil phosphoribosyltransferase -
I6G64_RS19050 4075706..4076995 + 1290 WP_063197301.1 uracil permease -
I6G64_RS19055 4077045..4077293 - 249 WP_004951888.1 GlsB/YeaQ/YmgE family stress response membrane protein -
I6G64_RS19060 4077332..4077847 - 516 WP_006327215.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10611.19 Da        Isoelectric Point: 6.0726

>T183166 WP_006316908.1 NZ_CP065673:4072625-4072894 [Serratia plymuthica]
MRIEWSREAQEELWNIIDYIDDRNPQAALILQREIETAVHSLSLNPFMYRLGRVDNTREIVVHPNYLIVYRIIGHIEVLG
VIHAKREYP

Download         Length: 270 bp

>T183166 NZ_CP086726:1822284-1822385 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7443.65 Da        Isoelectric Point: 10.2045

>AT183166 WP_013814083.1 NZ_CP065673:4072427-4072621 [Serratia plymuthica]
MVIKTSLSTQPTAEVAEQGESYDRWFRAKIEAAINSEKPRIPHEQVMNEMQIRLAAKKKIRKME

Download         Length: 195 bp

>AT183166 NZ_CP086726:c1822509-1822330 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1KUP0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U3Z4H1

References