Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 3000130..3000695 Replicon chromosome
Accession NZ_CP065673
Organism Serratia plymuthica strain FDAARGOS_907

Toxin (Protein)


Gene name relE Uniprot ID A0A2X4V4R7
Locus tag I6G64_RS14190 Protein ID WP_063200583.1
Coordinates 3000130..3000408 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A2X4VH61
Locus tag I6G64_RS14195 Protein ID WP_062868918.1
Coordinates 3000426..3000695 (-) Length 90 a.a.

Genomic Context

I6G64_RS14175I6G64_RS14180I6G64_RS14185I6G64_RS14200I6G64_RS14205I6G64_RS14210I6G64_RS14170I6G64_RS14190I6G64_RS14195
Location: 2996990..2997559 (570 bp)
Type: Others
Protein ID: WP_062868920.1
Location: 2997719..2999404 (1686 bp)
Type: Others
Protein ID: WP_197913203.1
Location: 2999404..3000129 (726 bp)
Type: Others
Protein ID: WP_197913204.1
Location: 3000925..3002451 (1527 bp)
Type: Others
Protein ID: WP_037433749.1
Location: 3002557..3003132 (576 bp)
Type: Others
Protein ID: WP_006328493.1
Location: 3003264..3004481 (1218 bp)
Type: Others
Protein ID: WP_062868917.1
Location: 2996295..2996633 (339 bp)
Type: Others
Protein ID: WP_041416656.1
Location: 3000130..3000408 (279 bp)
Type: Toxin
Protein ID: WP_063200583.1
Location: 3000426..3000695 (270 bp)
Type: Antitoxin
Protein ID: WP_062868918.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6G64_RS141702996295..2996633-339WP_041416656.1PTS lactose/cellobiose transporter subunit IIA-
I6G64_RS141752996990..2997559+570WP_062868920.1peptidylprolyl isomerase A-
I6G64_RS141802997719..2999404+1686WP_197913203.1sensor histidine kinase-
I6G64_RS141852999404..3000129+726WP_197913204.1two-component system response regulator BtsR-
I6G64_RS141903000130..3000408-279WP_063200583.1type II toxin-antitoxin system RelE/ParE family toxinToxin
I6G64_RS141953000426..3000695-270WP_062868918.1hypothetical proteinAntitoxin
I6G64_RS142003000925..3002451+1527WP_037433749.1DUF853 family protein-
I6G64_RS142053002557..3003132+576WP_006328493.1aminodeoxychorismate synthase component II-
I6G64_RS142103003264..3004481+1218WP_062868917.1aspartate aminotransferase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10260.87 Da        Isoelectric Point: 8.5141

>T183163 WP_063200583.1 NZ_CP065673:c3000408-3000130 [Serratia plymuthica]
VTLKWTEPAIADRMAIYDYLETKNPAAAIEIDSLISATATRLSQNPSSGKPGRVPGTREMVIHHSYFLVYELINGLIIML
AVVHARRQWPAN

Download         Length: 279 bp

>T183163 NZ_CP086726:c1662475-1662332 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10352.65 Da        Isoelectric Point: 7.0169

>AT183163 WP_062868918.1 NZ_CP065673:c3000695-3000426 [Serratia plymuthica]
MSESTVVIRVDEELKIAFASAAKAADRTASQLLRDFMRDFVSRQTHQKEYEQWLQEKVDLSRKALNEGKITDNEAVEAYF
AERRSKLTR

Download         Length: 270 bp

>AT183163 NZ_CP086726:c1662188-1662139 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2X4V4R7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2X4VH61

References