Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2396573..2397046 Replicon chromosome
Accession NZ_CP065673
Organism Serratia plymuthica strain FDAARGOS_907

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6G64_RS11500 Protein ID WP_063202450.1
Coordinates 2396573..2396848 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2X4TR66
Locus tag I6G64_RS11505 Protein ID WP_062869225.1
Coordinates 2396849..2397046 (-) Length 66 a.a.

Genomic Context

I6G64_RS11495I6G64_RS11515I6G64_RS11520I6G64_RS11525I6G64_RS11485I6G64_RS11490I6G64_RS11500I6G64_RS11505I6G64_RS11510I6G64_RS11530I6G64_RS11535
Location: 2394196..2396512 (2317 bp)
Type: Others
Protein ID: Protein_2234
Location: 2397573..2398238 (666 bp)
Type: Others
Protein ID: WP_006323048.1
Location: 2398281..2398715 (435 bp)
Type: Others
Protein ID: WP_063202452.1
Location: 2398796..2399359 (564 bp)
Type: Others
Protein ID: WP_004950949.1
Location: 2391617..2391994 (378 bp)
Type: Others
Protein ID: WP_063202448.1
Location: 2392050..2393513 (1464 bp)
Type: Others
Protein ID: WP_062869227.1
Location: 2396573..2396848 (276 bp)
Type: Toxin
Protein ID: WP_063202450.1
Location: 2396849..2397046 (198 bp)
Type: Antitoxin
Protein ID: WP_062869225.1
Location: 2397107..2397352 (246 bp)
Type: Others
Protein ID: WP_004950955.1
Location: 2399408..2400607 (1200 bp)
Type: Others
Protein ID: WP_063202454.1
Location: 2400604..2401857 (1254 bp)
Type: Others
Protein ID: WP_063202456.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6G64_RS114852391617..2391994-378WP_063202448.1AprI/Inh family metalloprotease inhibitor-
I6G64_RS114902392050..2393513-1464WP_062869227.1serralysin family metalloprotease-
I6G64_RS114952394196..2396512+2317Protein_2234zinc/cadmium/mercury/lead-transporting ATPase-
I6G64_RS115002396573..2396848-276WP_063202450.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
I6G64_RS115052396849..2397046-198WP_062869225.1hypothetical proteinAntitoxin
I6G64_RS115102397107..2397352-246WP_004950955.1sulfurtransferase TusA-
I6G64_RS115152397573..2398238+666WP_006323048.17-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter-
I6G64_RS115202398281..2398715+435WP_063202452.1GNAT family N-acetyltransferase-
I6G64_RS115252398796..2399359+564WP_004950949.1DcrB family lipoprotein-
I6G64_RS115302399408..2400607-1200WP_063202454.1anaerobic glycerol-3-phosphate dehydrogenase subunit C-
I6G64_RS115352400604..2401857-1254WP_063202456.1glycerol-3-phosphate dehydrogenase subunit GlpB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10660.56 Da        Isoelectric Point: 11.2606

>T183162 WP_063202450.1 NZ_CP065673:c2396848-2396573 [Serratia plymuthica]
MLVIEWSRSARQDLADILLFIANDNPRAARKMKVLISEAILPAAEHPHIFRRGRVDGTHEIIVHPNYLLIYQVVADRIRV
MRVLHARRRYP

Download         Length: 276 bp

>T183162 NZ_CP086726:1401396-1402034 [Enterococcus faecalis]
ATGATACTTAATAAGAAAAAATTATATTTCGAAACACAGGCATTTACTGACAAACTTATAAATGAAATTTCAATCAATAT
GTCTAAAAGAAAAGAACTCATCAATTGTTATGATATTGAAGCCTACGTAAAAGAAACCGAAAACATTGATTTTTTTGATT
ATCCATTCAAAAAACAATCTAAAAAATTAATCTGGGGATCAGTAACAAAAATTGGTGATGTAACTATGGTAGCGACTGCC
CAACACTTGAAAATAGAAATTAAAAATTTTACGAAAATGCACGAAATAATTCATCATTATTTTGACTATACGACAGATAT
ACCTAACAATGAAAAATCATTTGATACACTACTTATAAAAAAGGGCTATCTTCCTGAAGATTATCCTAAAGAATTCAGAG
CAAATAAGGGTGCCGGAATGTTACTTATTAATAAAAAAGCCTTAAAGTATGCATTTAGTACTTATGATGATCTTGAAAAA
ATGGCTAGTTTTTTCAACGTAAACGATATAGTTCTCAAGATAAGAATTCTTGACGAATTAATCTATTCCCACAACTTATC
TTATAAACAAGCCAATCTTATTTATAATAGTTACTATTTTCAACAACAAACACAACTTAAAGAGATTTTATTCAAATAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7580.65 Da        Isoelectric Point: 4.4488

>AT183162 WP_062869225.1 NZ_CP065673:c2397046-2396849 [Serratia plymuthica]
MVILRSPVVSEYETQEQTEIYDRWFREKVREAMDDPLPGISHDEVMAEMDALIAVAEARKKTKQV

Download         Length: 198 bp

>AT183162 NZ_CP086726:1401015-1401389 [Enterococcus faecalis]
ATGAAAACTTACGAAAAGATAAAACAATTAAGAGAAAATAGAGAAATCACTCAAAAAGAAATTTCAAACGCACTAGACAT
TAATGTTAGTGTATATAATAAAATAGAACTTGGAATACGTCCATTAAGAGAAGAAGAACTTACTGCTATTGCTGATTTTT
TTAATGTTTCAATTGATTATTTAACAGGACGCACTGATAACCCTACAACACCTTCAAATAATCAAAAAGAAGCTGGACAA
AATATTATTTCACATTTCAGATTAAACACTAATGATTTAAGTTCTGATGACATAGAAGAATTAGAAAAAGAATTGATTGA
TTTTCAAGAATTTCTTATAAAACGAGCAAAAGAAAGAAAAAAAAAGAGTGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2X4TR66

References