Detailed information of TA system TA183141

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RelE(toxin)
• Location: 3323825..3324390
• Replicon: chromosome
• Accession: NZ_CP065668
• Organism: Delftia acidovorans strain FDAARGOS_909

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: I6G66_RS15785
• Protein ID: WP_197957467.1
• Coordinates: 3323825..3324112 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: I6G66_RS15790
• Protein ID: WP_183021502.1
• Coordinates: 3324106..3324390 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6G66_RS15770	3320483..3321052	+	570	WP_034390445.1	VUT family protein	-
I6G66_RS15775	3321219..3322595	-	1377	WP_197953240.1	amidohydrolase	-
I6G66_RS15780	3322692..3323762	+	1071	WP_197953242.1	helix-turn-helix domain-containing protein	-
I6G66_RS15785	3323825..3324112	-	288	WP_197957467.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I6G66_RS15790	3324106..3324390	-	285	WP_183021502.1	hypothetical protein	Antitoxin
I6G66_RS15795	3324575..3325522	-	948	WP_183021501.1	LysR family transcriptional regulator	-
I6G66_RS15800	3325690..3326670	+	981	WP_197953244.1	tripartite tricarboxylate transporter substrate binding protein	-
I6G66_RS15805	3326714..3327907	+	1194	WP_197953246.1	CoA transferase	-
I6G66_RS15810	3327921..3328703	+	783	WP_183021498.1	enoyl-CoA hydratase/isomerase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10618.27 Da
• Isoelectric Point: 9.0421

>T183141 WP_197957467.1 NZ_CP065668:c3324112-3323825 [Delftia acidovorans]
IVKLVWTRPAAADRREIRAYIAHDNPSAALALDERFSEIAGCLIDHPLLGRVGRVAGTRELVVHPNYILVYDVIADSVRV
LRVLHAARQWPSQQA

Nucleotide

• Length: 288 bp

>T183141 NZ_CP086680:c10801-10520 [Escherichia coli]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10546.75 Da
• Isoelectric Point: 4.6677

>AT183141 WP_183021502.1 NZ_CP065668:c3324390-3324106 [Delftia acidovorans]
MSEATFTFRVDEALKSDFAIAAKACDRTGAQLLRDFMRSFVQQQEQAAAHDRWLREQVQAGIDAANAGEVLSADEVEAEA
QVWRTEMRRRIAAS

Nucleotide

• Length: 285 bp

>AT183141 NZ_CP086680:c11042-10791 [Escherichia coli]
ATGAGCTATCAAATTCTGACAACCACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA