Detailed information of TA system TA183126

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 3561233..3561774
• Replicon: chromosome
• Accession: NZ_CP065652
• Organism: Achromobacter xylosoxidans strain FDAARGOS_915

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: I6G72_RS16565
• Protein ID: WP_026384571.1
• Coordinates: 3561499..3561774 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: I6G72_RS16560
• Protein ID: WP_024069590.1
• Coordinates: 3561233..3561499 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6G72_RS16540	3556472..3556678	+	207	WP_006385007.1	hypothetical protein	-
I6G72_RS16545	3556731..3559157	-	2427	WP_070543066.1	TonB-dependent receptor	-
I6G72_RS16550	3559417..3560373	-	957	WP_054498804.1	FecR domain-containing protein	-
I6G72_RS16555	3560459..3560986	-	528	WP_024069591.1	sigma-70 family RNA polymerase sigma factor	-
I6G72_RS16560	3561233..3561499	+	267	WP_024069590.1	ribbon-helix-helix domain-containing protein	Antitoxin
I6G72_RS16565	3561499..3561774	+	276	WP_026384571.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I6G72_RS16570	3561780..3562217	-	438	WP_020928528.1	acetyltransferase	-
I6G72_RS16575	3562230..3563969	-	1740	WP_024069589.1	hypothetical protein	-
I6G72_RS16580	3564027..3564893	-	867	WP_024069588.1	ABC transporter permease	-
I6G72_RS16585	3564899..3565822	-	924	WP_006385014.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (8-45)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10710.42 Da
• Isoelectric Point: 10.4170

>T183126 WP_026384571.1 NZ_CP065652:3561499-3561774 [Achromobacter xylosoxidans]
MEMKWTSKALSDLARLHEFLAAVNRPAAVRAVQALVKASSVLPTNSRIGEQLFQFEPREVRRILVGEYEIRYEIRDSIIY
VLRLWHTRENR

Nucleotide

• Length: 276 bp

>T183126 NZ_CP086678:c1680484-1679936 [Escherichia coli]
ATGTCTCACAATTCAGATATCTATAAACTTATCGGAGCGGCCGCAGGTGTTGAAAATGGTCGCTCTGAAGCATCCTTAAA
CTCTACTGACAGTCAAGAACAGATTTTTAAATCTGCATTTGAGCCGTCTAATCATGAGAGCGACGATGATTCTTCTTCAG
AAAATAAAGCTATTCTGGAGGCAGAAGAGTTTGGTTCTAATACTGGTGCATTGCATGAGTTTATGCAGCAGAACAGAATG
GACAGTCTTCAAGCTCAGCTTGATATGCTCAAATCACAAGTACGGGATAAGATAGCTGACGCAACTGGTAAAGAAATAGA
CAATGAGCTTCGGACAAAAATGGCCTCATTCACGGTTTGGTTTATGTCGTGTTGGTGCTTATTCGTTGTCGCAATGTTTA
CATCGTTTCTTATTGCACATGAAGGAAAGCCTCCAGTTGAAGCGATCGTTGCATTACTAGGTACAAGTACAATTAGTATT
GTTGGTTTGGTTGGTTTCGTTGTTAGTGGATTGTTCAAATCAAGAAAAGATAGTGATAAAGAAAAATAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9699.04 Da
• Isoelectric Point: 4.5720

>AT183126 WP_024069590.1 NZ_CP065652:3561233-3561499 [Achromobacter xylosoxidans]
MSPATKVLTAHVPLPLAEKVDQMAVRLDRSRGWIVKQALSAWIAQEEERDKLTEQALADVDAGRIVDDQAVQAWAESLGS
DQPLPLPR

Nucleotide

• Length: 267 bp

>AT183126 NZ_CP086678:c1680980-1680507 [Escherichia coli]
ATGTACAGCCCGGTACAAATAGCCAATAAATTCATAACGTTGGGAAACCAACATCATAATCCTCTGACCCACATGCAACT
GCAGAAGCTTACTTATATTGCACATGGTTACTATTTAGCATTAACAGGTAAGCCTTTGCTCAATGAATGTGTCTCCGCGT
GGAAGTACGGTCCAGTTATTCCTGGAATGTACGATGCTTTCAAAGATTATGGGAATAAACCTGTTACGAATGTAGCAGTA
GCTCCTTTTGGTGGCATTGTTACTATGGATCCACAAGCAGAGAGCATTATAGGGGCTGTTTATAAATTTTACGGCTCGAA
AAATGGAATTGAGTTATCAACTCTAACTCATATGCCTGGTACGCCTTGGTCACAAGCTTATAATGGTATTGGCTCGTCAA
TCATCTCAAATGATGCGATCAAGGCTTATTATCATGATTTATTGAATAACCGACAGCAATGTCAGGGCCTCTGA