Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 921284..921963 Replicon chromosome
Accession NZ_CP065627
Organism Delftia acidovorans strain FDAARGOS_939

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I6G96_RS04150 Protein ID WP_180318716.1
Coordinates 921284..921709 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I6G96_RS04155 Protein ID WP_180318715.1
Coordinates 921706..921963 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G96_RS04125 916424..916915 + 492 WP_123695671.1 type II toxin-antitoxin system YhaV family toxin -
I6G96_RS04130 916930..917442 - 513 WP_012207634.1 MgtC/SapB family protein -
I6G96_RS04135 917558..919003 - 1446 WP_197944356.1 chloride channel protein -
I6G96_RS04140 919161..920054 - 894 WP_013800520.1 LysR family transcriptional regulator -
I6G96_RS04145 920196..921245 + 1050 WP_197944357.1 NAD(P)-dependent alcohol dehydrogenase -
I6G96_RS04150 921284..921709 - 426 WP_180318716.1 type II toxin-antitoxin system VapC family toxin Toxin
I6G96_RS04155 921706..921963 - 258 WP_180318715.1 plasmid stability protein stbC Antitoxin
I6G96_RS04160 922067..922864 - 798 WP_197944358.1 precorrin-6A synthase (deacetylating) -
I6G96_RS04165 922861..923739 - 879 WP_065347781.1 precorrin-4 C(11)-methyltransferase -
I6G96_RS04170 923736..924224 - 489 WP_071957235.1 cobalamin biosynthesis protein -
I6G96_RS04175 924221..925423 - 1203 WP_197944359.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
I6G96_RS04180 925422..926207 + 786 WP_192368296.1 cobalt-precorrin-6A reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15222.47 Da        Isoelectric Point: 5.6390

>T183091 WP_180318716.1 NZ_CP065627:c921709-921284 [Delftia acidovorans]
MIVVDTNVISELWRLAPDSRVLAWMDAQAIETLHLSAVTVAELRYGIAAMPEGRRRTIYQERLEHEVLPAFAGRVLAFDL
DAAKAYADLMASAKTQGRAIAKADGYIAATAMAHGLVVATRDTSPFEAGGLQTINPWTAAP

Download         Length: 426 bp

>T183091 NZ_CP086662:c2801829-2801722 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAACGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9345.53 Da        Isoelectric Point: 6.7279

>AT183091 WP_180318715.1 NZ_CP065627:c921963-921706 [Delftia acidovorans]
MANVTVRNLPDAVHRALRVRAAHHGRSTEAEIRDILEAAVRPAERVRLGSMLASIAREAGGLTDSEAEGFNRLRDRAPAE
PMDFE

Download         Length: 258 bp

>AT183091 NZ_CP086662:2801877-2801943 [Escherichia coli]
GGTCTAGATGCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References