Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 19133..19364 Replicon chromosome
Accession NZ_CP065624
Organism Escherichia coli strain FDAARGOS_941

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 19134..19237 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 19133..19364 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6G98_RS00875 14702..15858 + 1157 WP_085948186.1 IS3-like element IS600 family transposase -
I6G98_RS00880 15870..16067 + 198 WP_197932993.1 hypothetical protein -
I6G98_RS00885 16118..16306 + 189 WP_000276806.1 DUF1187 family protein -
- 16124..16302 - 179 NuclAT_2 - -
- 16124..16302 - 179 NuclAT_2 - -
- 16124..16302 - 179 NuclAT_2 - -
- 16124..16302 - 179 NuclAT_2 - -
I6G98_RS00890 16413..16694 + 282 WP_005127484.1 excisionase -
I6G98_RS00895 16660..17184 + 525 Protein_26 phage integrase Arm DNA-binding domain-containing protein -
I6G98_RS00900 18122..18123 - 2 WP_085948182.1 IS3-like element IS600 family transposase -
I6G98_RS00905 18442..19002 + 561 Protein_28 tyrosine-type recombinase/integrase -
- 19133..19364 + 232 - - Antitoxin
- 19134..19237 - 104 - - Toxin
I6G98_RS00910 19394..19735 - 342 WP_000976478.1 YebY family protein -
I6G98_RS00915 19748..20620 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
I6G98_RS00920 20624..20998 - 375 WP_000168747.1 CopC domain-containing protein YobA -
I6G98_RS00925 21137..21367 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I6G98_RS00930 21469..22125 + 657 WP_032359391.1 carbon-nitrogen hydrolase family protein -
I6G98_RS00935 22149..22811 + 663 Protein_34 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T183055 NZ_CP065624:c19237-19134 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT183055 NZ_CP065624:19133-19364 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References