Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 825282..825516 | Replicon | chromosome |
| Accession | NZ_CP065615 | ||
| Organism | Escherichia coli strain FDAARGOS_943 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 825412..825515 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 825282..825516 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6H00_RS04290 | 821837..822499 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| I6H00_RS04295 | 822523..823179 | - | 657 | WP_000011660.1 | carbon-nitrogen hydrolase family protein | - |
| I6H00_RS04300 | 823281..823511 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I6H00_RS04305 | 823650..824024 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| I6H00_RS04310 | 824028..824900 | + | 873 | WP_197939913.1 | copper homeostasis membrane protein CopD | - |
| I6H00_RS04315 | 824913..825254 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 825282..825516 | - | 235 | - | - | Antitoxin |
| - | 825412..825515 | + | 104 | - | - | Toxin |
| I6H00_RS04320 | 825647..826723 | - | 1077 | WP_197939914.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| I6H00_RS04325 | 826689..826970 | - | 282 | WP_005127484.1 | excisionase | - |
| I6H00_RS04330 | 827077..827265 | - | 189 | WP_000276808.1 | DUF1187 family protein | - |
| - | 827081..827259 | + | 179 | NuclAT_0 | - | - |
| - | 827081..827259 | + | 179 | NuclAT_0 | - | - |
| - | 827081..827259 | + | 179 | NuclAT_0 | - | - |
| - | 827081..827259 | + | 179 | NuclAT_0 | - | - |
| I6H00_RS04335 | 827316..828413 | - | 1098 | WP_001173292.1 | AAA family ATPase | - |
| I6H00_RS04340 | 828419..828715 | - | 297 | WP_001277359.1 | host-nuclease inhibitor protein Gam | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / ipaH9.8 | 753575..874366 | 120791 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T183029 NZ_CP065615:825412-825515 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT183029 NZ_CP065615:c825516-825282 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
