Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 475402..475633 Replicon chromosome
Accession NZ_CP065611
Organism Escherichia coli strain FDAARGOS_945

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 475403..475506 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 475402..475633 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H02_RS02985 470482..471573 + 1092 WP_115264499.1 AAA family ATPase -
I6H02_RS02990 471624..471692 + 69 Protein_466 DUF1187 family protein -
- 472939..473061 - 123 NuclAT_1 - -
- 472939..473061 - 123 NuclAT_1 - -
- 472939..473061 - 123 NuclAT_1 - -
- 472939..473061 - 123 NuclAT_1 - -
I6H02_RS03000 472940..473065 + 126 Protein_468 DUF1187 family protein -
I6H02_RS03005 473172..473453 + 282 WP_005127484.1 excisionase -
I6H02_RS03010 473419..474495 + 1077 WP_052993702.1 phage integrase Arm DNA-binding domain-containing protein -
I6H02_RS03015 474556..475253 + 698 Protein_471 IS1 family transposase -
- 475402..475633 + 232 - - Antitoxin
- 475403..475506 - 104 - - Toxin
I6H02_RS03020 475663..476004 - 342 WP_115264500.1 YebY family protein -
I6H02_RS03025 476017..476889 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
I6H02_RS03030 476893..477267 - 375 WP_000168750.1 CopC domain-containing protein YobA -
I6H02_RS03035 477406..477636 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I6H02_RS03040 477738..478394 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
I6H02_RS03045 478418..479080 + 663 WP_000944263.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T182978 NZ_CP065611:c475506-475403 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 232 bp

>AT182978 NZ_CP065611:475402-475633 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References