Detailed information of TA system TA182932

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virT-relB/YafQ-DinJ
• Location: 895342..895885
• Replicon: chromosome
• Accession: NZ_CP065588
• Organism: Mycoplasma mycoides subsp. capri strain M-5

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: I7634_RS03835
• Protein ID: WP_265492870.1
• Coordinates: 895607..895885 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: I7634_RS03830
• Protein ID: WP_265492869.1
• Coordinates: 895342..895614 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I7634_RS03820 (I7634_03785)	891114..894155	-	3042	WP_265492867.1	viral A-type inclusion protein	-
I7634_RS03825 (I7634_03790)	894526..895098	+	573	WP_265492868.1	Fic family protein	-
I7634_RS03830 (I7634_03795)	895342..895614	+	273	WP_265492869.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
I7634_RS03835 (I7634_03800)	895607..895885	+	279	WP_265492870.1	type II toxin-antitoxin system YafQ family toxin	Toxin
I7634_RS03840 (I7634_03805)	896035..897446	+	1412	WP_265492651.1	IS3 family transposase	-
I7634_RS03845 (I7634_03810)	897550..898635	-	1086	WP_265492871.1	MupG family TIM beta-alpha barrel fold protein	-
I7634_RS03850 (I7634_03815)	898637..900025	-	1389	WP_265492873.1	glycoside hydrolase family 1 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-72)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10844.91 Da
• Isoelectric Point: 9.9130

>T182932 WP_265492870.1 NZ_CP065588:895607-895885 [Mycoplasma mycoides subsp. capri]
MIKYTILTTTKFIKDLKLAKKQNKNLEKLDIIINKLENDEILDKKYKDHPLTGKYEGYRECHIEPDLLIYKKEKKDLLLV
LFRLGSHSKIL

Nucleotide

• Length: 279 bp

>T182932 NZ_CP086622:2417808-2417911 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10381.77 Da
• Isoelectric Point: 4.5609

>AT182932 WP_265492869.1 NZ_CP065588:895342-895614 [Mycoplasma mycoides subsp. capri]
VKTTNVNIKMDPEIKKQASLLFKEFGMTMSSAINLFVKTAVEQNDIPFEYNREITNKETLEAFEEGERLLADKNAKRYSS
FKEILDSLDD

Nucleotide

• Length: 273 bp

>AT182932 NZ_CP086622:c2417949-2417678 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT