Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virT-relB/YafQ-DinJ
Location 977268..977811 Replicon chromosome
Accession NZ_CP065575
Organism Mycoplasma mycoides subsp. capri strain My-I

Toxin (Protein)


Gene name virT Uniprot ID -
Locus tag I7632_RS04310 Protein ID WP_265492870.1
Coordinates 977533..977811 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I7632_RS04305 Protein ID WP_265492869.1
Coordinates 977268..977540 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I7632_RS04295 (I7632_04165) 973040..976081 - 3042 WP_265492867.1 viral A-type inclusion protein -
I7632_RS04300 (I7632_04170) 976452..977024 + 573 WP_265492868.1 Fic family protein -
I7632_RS04305 (I7632_04175) 977268..977540 + 273 WP_265492869.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I7632_RS04310 (I7632_04180) 977533..977811 + 279 WP_265492870.1 type II toxin-antitoxin system YafQ family toxin Toxin
I7632_RS04315 (I7632_04185) 977988..979073 - 1086 WP_265492871.1 MupG family TIM beta-alpha barrel fold protein -
I7632_RS04320 (I7632_04190) 979075..980463 - 1389 WP_265492873.1 glycoside hydrolase family 1 protein -
I7632_RS04325 (I7632_04195) 980456..981334 - 879 WP_265492874.1 ROK family protein -
I7632_RS04330 (I7632_04200) 981336..981794 - 459 WP_265492875.1 PTS sugar transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-72)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10844.91 Da        Isoelectric Point: 9.9130

>T182925 WP_265492870.1 NZ_CP065575:977533-977811 [Mycoplasma mycoides subsp. capri]
MIKYTILTTTKFIKDLKLAKKQNKNLEKLDIIINKLENDEILDKKYKDHPLTGKYEGYRECHIEPDLLIYKKEKKDLLLV
LFRLGSHSKIL

Download         Length: 279 bp

>T182925 NZ_CP086622:263239-263346 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CATGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10381.77 Da        Isoelectric Point: 4.5609

>AT182925 WP_265492869.1 NZ_CP065575:977268-977540 [Mycoplasma mycoides subsp. capri]
VKTTNVNIKMDPEIKKQASLLFKEFGMTMSSAINLFVKTAVEQNDIPFEYNREITNKETLEAFEEGERLLADKNAKRYSS
FKEILDSLDD

Download         Length: 273 bp

>AT182925 NZ_CP086622:c263190-263127 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References