Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1981..2540 Replicon plasmid pR16.1424_p82k
Accession NZ_CP065573
Organism Salmonella enterica subsp. enterica serovar Albany strain R16.1424

Toxin (Protein)


Gene name relE Uniprot ID U9YB49
Locus tag I7655_RS23415 Protein ID WP_000421259.1
Coordinates 2265..2540 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U9Y625
Locus tag I7655_RS23410 Protein ID WP_001178087.1
Coordinates 1981..2265 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I7655_RS23405 46..1077 + 1032 WP_000907852.1 replication initiation protein -
I7655_RS23410 1981..2265 + 285 WP_001178087.1 ribbon-helix-helix protein, CopG family Antitoxin
I7655_RS23415 2265..2540 + 276 WP_000421259.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I7655_RS23420 2646..2927 + 282 WP_001105066.1 hypothetical protein -
I7655_RS23425 3119..3385 - 267 WP_000627832.1 hypothetical protein -
I7655_RS23430 3385..3879 - 495 WP_015058884.1 hypothetical protein -
I7655_RS23435 3935..4537 - 603 WP_197931348.1 proQ/FINO family protein -
I7655_RS23440 4713..5765 - 1053 WP_000655519.1 hypothetical protein -
I7655_RS23445 5978..6568 - 591 WP_001401589.1 hypothetical protein -
I7655_RS23450 6568..6822 - 255 WP_000343106.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..84218 84218


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T182923 WP_000421259.1 NZ_CP065573:2265-2540 [Salmonella enterica subsp. enterica serovar Albany]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp

>T182923 NZ_CP086622:262272-262379 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT182923 WP_001178087.1 NZ_CP065573:1981-2265 [Salmonella enterica subsp. enterica serovar Albany]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT182923 NZ_CP086622:c262223-262160 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB U9YB49

Antitoxin

Source ID Structure
AlphaFold DB U9Y625

References