182906

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014701..2014846 Replicon chromosome
Accession NZ_CP065554
Organism Klebsiella pneumoniae strain FK 6768

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014737..2014839 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014701..2014846 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I7S93_RS09855 (I7S93_09855) 2009831..2011891 + 2061 WP_004151449.1 oligopeptidase B -
I7S93_RS09860 (I7S93_09860) 2011895..2012554 - 660 WP_002911407.1 exodeoxyribonuclease X -
I7S93_RS09865 (I7S93_09865) 2012633..2012863 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I7S93_RS09870 (I7S93_09870) 2012976..2013350 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I7S93_RS09875 (I7S93_09875) 2013354..2014223 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
I7S93_RS09880 (I7S93_09880) 2014240..2014578 + 339 WP_002911404.1 YebY family protein -
- 2014701..2014846 - 146 - - Antitoxin
- 2014737..2014839 + 103 - - Toxin
I7S93_RS09885 (I7S93_09885) 2015214..2015357 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I7S93_RS09890 (I7S93_09890) 2015462..2016430 - 969 WP_004151446.1 VirK/YbjX family protein -
I7S93_RS09895 (I7S93_09895) 2016587..2017240 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
I7S93_RS09900 (I7S93_09900) 2017237..2017428 - 192 WP_002911395.1 YebW family protein -
I7S93_RS09905 (I7S93_09905) 2017526..2017765 - 240 WP_002911393.1 YebV family protein -
I7S93_RS09910 (I7S93_09910) 2017881..2019314 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182906 NZ_CP065554:2014737-2014839 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182906 NZ_CP065554:c2014846-2014701 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References