Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3152065..3152728 Replicon chromosome
Accession NZ_CP065534
Organism Lonsdalea populi strain N-5-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag I6N93_RS13755 Protein ID WP_085688707.1
Coordinates 3152065..3152481 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag I6N93_RS13760 Protein ID WP_085688773.1
Coordinates 3152462..3152728 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6N93_RS13735 3147701..3148600 - 900 WP_085688715.1 site-specific tyrosine recombinase XerD -
I6N93_RS13740 3148853..3150181 + 1329 WP_085688776.1 MHS family MFS transporter -
I6N93_RS13745 3150340..3150873 + 534 WP_085688712.1 flavodoxin FldB -
I6N93_RS13750 3150935..3151888 - 954 WP_085688709.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
I6N93_RS13755 3152065..3152481 - 417 WP_085688707.1 protein YgfX Toxin
I6N93_RS13760 3152462..3152728 - 267 WP_085688773.1 FAD assembly factor SdhE Antitoxin
I6N93_RS13765 3152960..3153940 + 981 WP_085688705.1 tRNA-modifying protein YgfZ -
I6N93_RS13770 3153965..3154612 - 648 WP_085688703.1 hemolysin III family protein -
I6N93_RS13775 3154845..3155447 + 603 WP_085688770.1 HD domain-containing protein -
I6N93_RS13780 3155508..3156830 - 1323 WP_085688700.1 MHS family MFS transporter -
I6N93_RS13785 3156830..3157480 - 651 WP_085688697.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16113.02 Da        Isoelectric Point: 11.7965

>T182888 WP_085688707.1 NZ_CP065534:c3152481-3152065 [Lonsdalea populi]
VAQWQCDLKVSWRMQLFSLLVHGIMVLLILLAPWPSGYAPLWLGLVSLVMFGFIRSQRNIKSRHGAISLHGERRLRWQQR
EWRIVKRPWMLKSGILLSLRAADGAAQEQRLWLSSDSMGRDEWRHLRQLLLQKDSCAG

Download         Length: 417 bp

>T182888 NZ_CP086618:c4460662-4460375 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10476.90 Da        Isoelectric Point: 6.0666

>AT182888 WP_085688773.1 NZ_CP065534:c3152728-3152462 [Lonsdalea populi]
MDINDKSRIHWACRRGMRELDISIMPFFEHDYDTLNDSDKNAFVRLLQCDDPDLFNWLMNHGEPSDQELKRMVSLIQTRN
KHRGPVAM

Download         Length: 267 bp

>AT182888 NZ_CP086618:c4460388-4460086 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References