Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 84089..84714 Replicon chromosome
Accession NZ_CP065534
Organism Lonsdalea populi strain N-5-1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag I6N93_RS00370 Protein ID WP_085686901.1
Coordinates 84089..84496 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag I6N93_RS00375 Protein ID WP_085686903.1
Coordinates 84493..84714 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6N93_RS00360 79604..80878 + 1275 WP_085686897.1 HlyD family secretion protein -
I6N93_RS00365 80871..82982 + 2112 WP_085686899.1 peptidase domain-containing ABC transporter -
I6N93_RS00370 84089..84496 - 408 WP_085686901.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
I6N93_RS00375 84493..84714 - 222 WP_085686903.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
I6N93_RS00380 85041..85904 - 864 WP_085686905.1 YicC family protein -
I6N93_RS00385 86164..87072 - 909 WP_085686907.1 LysR family transcriptional regulator -
I6N93_RS00390 87222..88298 - 1077 WP_085686909.1 dipeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15239.30 Da        Isoelectric Point: 5.1499

>T182883 WP_085686901.1 NZ_CP065534:c84496-84089 [Lonsdalea populi]
MIWISAQEVIAFHDRILQRLPGVAGITDPGRAEALIYRVQNRAHYEGTTDIFELAATYWVAIARGHIFNDGNKRTAFFVT
MTFLYRNGVKIRDNDNALENLTVEAATGEKTVIQLAQSLRDLMDNFNPTDLIPVD

Download         Length: 408 bp

>T182883 NZ_CP086618:3193950-3194444 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8153.97 Da        Isoelectric Point: 5.0631

>AT182883 WP_085686903.1 NZ_CP065534:c84714-84493 [Lonsdalea populi]
MRTYTSTQARANISEVLDAATHGEAVEITRRDGSSAVVISKTEFEAYQNAKLDAEFEEIMQRHGHTVEALTNR

Download         Length: 222 bp

>AT182883 NZ_CP086618:3193660-3193953 [Escherichia coli]
ATGCCAGCAGCCAATAACATTCCAACCAGGCGCGAATCTTTAAATTTGCGCATAAAACCCGCAGAACGCGATCTTATTGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCACCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References