Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1865271..1865800 Replicon plasmid megaplasmid
Accession NZ_CP065532
Organism Ralstonia solanacearum strain 362200

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IMF25_RS24610 Protein ID WP_016722340.1
Coordinates 1865573..1865800 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IMF25_RS24605 Protein ID WP_016722339.1
Coordinates 1865271..1865576 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMF25_RS24575 1860769..1861254 + 486 WP_016726511.1 hypothetical protein -
IMF25_RS24580 1861585..1861866 - 282 WP_019719760.1 hypothetical protein -
IMF25_RS24585 1861999..1862283 - 285 WP_111375044.1 hypothetical protein -
IMF25_RS24590 1862588..1862805 + 218 Protein_1480 transposase -
IMF25_RS24595 1862972..1863640 + 669 WP_038938024.1 hypothetical protein -
IMF25_RS24600 1863745..1865058 - 1314 WP_038938025.1 metabolite/H+ symporter -
IMF25_RS24605 1865271..1865576 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
IMF25_RS24610 1865573..1865800 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IMF25_RS24615 1865955..1867154 - 1200 WP_016726513.1 MFS transporter -
IMF25_RS24620 1867281..1868102 - 822 WP_011003398.1 GntR family transcriptional regulator -
IMF25_RS24625 1868280..1868831 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
IMF25_RS24630 1868964..1869563 + 600 WP_016722344.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliG / fliI / acrB / htpB / adeG / cheY / cheB / cheW / motA 1..2034020 2034020


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T182881 WP_016722340.1 NZ_CP065532:c1865800-1865573 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T182881 NZ_CP086618:3019048-3019155 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT182881 WP_016722339.1 NZ_CP065532:c1865576-1865271 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT182881 NZ_CP086618:c3019001-3018935 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References