Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2313232..2313377 Replicon chromosome
Accession NZ_CP065460
Organism Klebsiella pneumoniae strain Gordon

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2313268..2313370 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2313232..2313377 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5M58_RS11360 2308362..2310422 + 2061 WP_004151449.1 oligopeptidase B -
I5M58_RS11365 2310426..2311085 - 660 WP_002911407.1 exodeoxyribonuclease X -
I5M58_RS11370 2311164..2311394 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5M58_RS11375 2311507..2311881 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I5M58_RS11380 2311885..2312754 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
I5M58_RS11385 2312771..2313109 + 339 WP_002911404.1 YebY family protein -
- 2313232..2313377 - 146 - - Antitoxin
- 2313268..2313370 + 103 - - Toxin
I5M58_RS11390 2313745..2313888 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I5M58_RS11395 2313993..2314961 - 969 WP_194315551.1 VirK/YbjX family protein -
I5M58_RS11400 2315118..2315771 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
I5M58_RS11405 2315768..2315959 - 192 WP_002911395.1 YebW family protein -
I5M58_RS11410 2316057..2316296 - 240 WP_002911393.1 YebV family protein -
I5M58_RS11415 2316412..2317845 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182769 NZ_CP065460:2313268-2313370 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182769 NZ_CP065460:c2313377-2313232 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References