Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3037097..3037242 Replicon chromosome
Accession NZ_CP065457
Organism Klebsiella pneumoniae strain Magic conch shell

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3037104..3037206 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3037097..3037242 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5M59_RS14800 3032628..3034061 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I5M59_RS14805 3034177..3034416 + 240 WP_002911393.1 YebV family protein -
I5M59_RS14810 3034514..3034705 + 192 WP_002911395.1 YebW family protein -
I5M59_RS14815 3034702..3035355 - 654 WP_023280291.1 protein-serine/threonine phosphatase -
I5M59_RS14820 3035512..3036480 + 969 WP_004151446.1 VirK/YbjX family protein -
I5M59_RS14825 3036585..3036728 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3037097..3037242 + 146 - - Antitoxin
- 3037104..3037206 - 103 - - Toxin
I5M59_RS14830 3037365..3037703 - 339 WP_002911404.1 YebY family protein -
I5M59_RS14835 3037720..3038589 - 870 WP_023285313.1 copper homeostasis membrane protein CopD -
I5M59_RS14840 3038593..3038967 - 375 WP_023285314.1 CopC domain-containing protein YobA -
I5M59_RS14845 3039080..3039310 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I5M59_RS14850 3039389..3040048 + 660 WP_002911407.1 exodeoxyribonuclease X -
I5M59_RS14855 3040052..3042112 - 2061 WP_047694778.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182750 NZ_CP065457:c3037206-3037104 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182750 NZ_CP065457:3037097-3037242 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References