Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 677875..678020 Replicon chromosome
Accession NZ_CP065447
Organism Klebsiella pneumoniae strain Ocean Ranger

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 677911..678013 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 677875..678020 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5M61_RS03150 673005..675065 + 2061 WP_004151449.1 oligopeptidase B -
I5M61_RS03155 675069..675728 - 660 WP_002911407.1 exodeoxyribonuclease X -
I5M61_RS03160 675807..676037 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5M61_RS03165 676150..676524 + 375 WP_039819395.1 CopC domain-containing protein YobA -
I5M61_RS03170 676528..677397 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I5M61_RS03175 677414..677752 + 339 WP_002911404.1 YebY family protein -
- 677875..678020 - 146 - - Antitoxin
- 677911..678013 + 103 - - Toxin
I5M61_RS03180 678388..678531 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
I5M61_RS03185 678636..679604 - 969 WP_014907334.1 VirK/YbjX family protein -
I5M61_RS03190 679761..680414 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
I5M61_RS03195 680411..680602 - 192 WP_002911395.1 YebW family protein -
I5M61_RS03200 680700..680939 - 240 WP_002911393.1 YebV family protein -
I5M61_RS03205 681055..682488 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182703 NZ_CP065447:677911-678013 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182703 NZ_CP065447:c678020-677875 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References