Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3177521..3177666 Replicon chromosome
Accession NZ_CP065444
Organism Klebsiella pneumoniae strain Sea Superman

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3177528..3177630 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3177521..3177666 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5M62_RS15790 3173053..3174486 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I5M62_RS15795 3174602..3174841 + 240 WP_002911393.1 YebV family protein -
I5M62_RS15800 3174939..3175130 + 192 WP_002911395.1 YebW family protein -
I5M62_RS15805 3175127..3175780 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
I5M62_RS15810 3175937..3176905 + 969 WP_004151446.1 VirK/YbjX family protein -
I5M62_RS15815 3177010..3177153 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3177521..3177666 + 146 - - Antitoxin
- 3177528..3177630 - 103 - - Toxin
I5M62_RS15820 3177789..3178127 - 339 WP_002911404.1 YebY family protein -
I5M62_RS15825 3178144..3179013 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
I5M62_RS15830 3179017..3179391 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I5M62_RS15835 3179504..3179734 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I5M62_RS15840 3179813..3180472 + 660 WP_002911407.1 exodeoxyribonuclease X -
I5M62_RS15845 3180476..3182536 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182684 NZ_CP065444:c3177630-3177528 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182684 NZ_CP065444:3177521-3177666 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References