Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 666712..666857 Replicon chromosome
Accession NZ_CP065436
Organism Klebsiella pneumoniae strain Dirty Dan

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 666748..666850 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 666712..666857 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6Z21_RS03160 661842..663902 + 2061 WP_004151449.1 oligopeptidase B -
I6Z21_RS03165 663906..664565 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6Z21_RS03170 664644..664874 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6Z21_RS03175 664987..665361 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6Z21_RS03180 665365..666234 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
I6Z21_RS03185 666251..666589 + 339 WP_016529031.1 YebY family protein -
- 666712..666857 - 146 - - Antitoxin
- 666748..666850 + 103 - - Toxin
I6Z21_RS03190 667225..667368 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6Z21_RS03195 667473..668441 - 969 WP_004151446.1 VirK/YbjX family protein -
I6Z21_RS03200 668598..669251 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
I6Z21_RS03205 669248..669439 - 192 WP_002911395.1 YebW family protein -
I6Z21_RS03210 669537..669776 - 240 WP_002911393.1 YebV family protein -
I6Z21_RS03215 669892..671325 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182616 NZ_CP065436:666748-666850 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182616 NZ_CP065436:c666857-666712 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References