Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3638614..3639518 Replicon chromosome
Accession NZ_CP065411
Organism Kosakonia radicincitans strain IAC-BECa95

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag I5960_RS17700 Protein ID WP_007374122.1
Coordinates 3639054..3639518 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag I5960_RS17695 Protein ID WP_007374123.1
Coordinates 3638614..3639057 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5960_RS17675 3633665..3635431 + 1767 WP_035885863.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD -
I5960_RS17680 3635432..3637153 + 1722 WP_227135782.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
I5960_RS17685 3637259..3637963 + 705 WP_035885865.1 leucyl/phenylalanyl-tRNA--protein transferase -
I5960_RS17690 3638247..3638465 + 219 WP_001040187.1 translation initiation factor IF-1 -
I5960_RS17695 3638614..3639057 + 444 WP_007374123.1 DUF2384 domain-containing protein Antitoxin
I5960_RS17700 3639054..3639518 + 465 WP_007374122.1 RES domain-containing protein Toxin
I5960_RS17705 3639640..3641928 - 2289 WP_035885867.1 ATP-dependent Clp protease ATP-binding subunit ClpA -
I5960_RS17710 3641960..3642280 - 321 WP_007374120.1 ATP-dependent Clp protease adapter ClpS -
I5960_RS17715 3642609..3642830 + 222 WP_007374119.1 cold shock-like protein CspD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(29-90)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17044.40 Da        Isoelectric Point: 6.0751

>T182575 WP_007374122.1 NZ_CP065411:3639054-3639518 [Kosakonia radicincitans]
VIFYRLVSRRYASEAWTGSGANQYGGRWNHKGHPAVYIASSVSLAALEMLVHVRSDTILSQYGLFSIDIPDKEIEYLDKQ
WLPPDWQENPAPLSTMDLGTAWLEANSAVALVVPSCVIPLENNAILNPQHAGFSKLLKSVKELPFSFDARLASS

Download         Length: 465 bp

>T182575 NZ_CP086500:1907831-1908085 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16407.90 Da        Isoelectric Point: 9.9132

>AT182575 WP_007374123.1 NZ_CP065411:3638614-3639057 [Kosakonia radicincitans]
MRTWSPEQKPVENALWRFAGFPANRGIKLVQMLNEGLPVSILDNIHEWTEMSRSDILRVTGINERNVARRKSAGRTLTPE
ESERIARLVRVIDAAVQFFGDKKMAYAWLQAPVRGLGNVAPISLIATESGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT182575 NZ_CP086500:1907583-1907834 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References