Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 919259..919922 Replicon chromosome
Accession NZ_CP065411
Organism Kosakonia radicincitans strain IAC-BECa95

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag I5960_RS04615 Protein ID WP_007370254.1
Coordinates 919506..919922 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag I5960_RS04610 Protein ID WP_007370253.1
Coordinates 919259..919525 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5960_RS04590 914703..916136 - 1434 WP_144134010.1 6-phospho-beta-glucosidase BglA -
I5960_RS04595 916252..916980 - 729 WP_227136833.1 MurR/RpiR family transcriptional regulator -
I5960_RS04600 917332..917991 + 660 WP_007370251.1 hemolysin III family protein -
I5960_RS04605 918031..919011 - 981 WP_007370252.1 tRNA-modifying protein YgfZ -
I5960_RS04610 919259..919525 + 267 WP_007370253.1 FAD assembly factor SdhE Antitoxin
I5960_RS04615 919506..919922 + 417 WP_007370254.1 protein YgfX Toxin
I5960_RS04620 919941..920462 - 522 WP_007370255.1 flavodoxin FldB -
I5960_RS04625 920563..921459 + 897 WP_035889602.1 site-specific tyrosine recombinase XerD -
I5960_RS04630 921484..922197 + 714 WP_007370257.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
I5960_RS04635 922203..923936 + 1734 WP_227136399.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16350.31 Da        Isoelectric Point: 10.7373

>T182564 WP_007370254.1 NZ_CP065411:919506-919922 [Kosakonia radicincitans]
VVLWQSELRVSWRAQWISLLLHGLGAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGELKLLMDSRLRWQGM
EWDIIGTPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRVISQKPAQGLH

Download         Length: 417 bp

>T182564 NZ_CP086493:67778-68158 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACGGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCTCCCGTGCTGGTGGAACTTGCGGTGGGGGCCGCAACAGG
TGAAATCCCCGTATCTTCAGTAGCGGAAAAACTACGTGAATTATTTGGTTCCAATATTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10557.98 Da        Isoelectric Point: 5.1069

>AT182564 WP_007370253.1 NZ_CP065411:919259-919525 [Kosakonia radicincitans]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQLFVRLLESDDPDLFNWLMNHGKPQDTELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT182564 NZ_CP086493:67557-67778 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGAGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTTGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References