Detailed information of TA system TA182562

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 3446202..3446670
• Replicon: chromosome
• Accession: NZ_CP065410
• Organism: Pseudomonas sp. IAC-BECa141

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: I5961_RS15665
• Protein ID: WP_234206646.1
• Coordinates: 3446434..3446670 (+)
• Length: 79 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: I5961_RS15660
• Protein ID: WP_085701856.1
• Coordinates: 3446202..3446396 (+)
• Length: 65 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I5961_RS15640 (I5961_15535)	3441834..3442802	-	969	WP_227232774.1	Gfo/Idh/MocA family oxidoreductase	-
I5961_RS15645 (I5961_15540)	3442812..3443699	-	888	WP_227232775.1	Dyp-type peroxidase	-
I5961_RS15650 (I5961_15545)	3443756..3444790	-	1035	WP_227232776.1	AraC family transcriptional regulator	-
I5961_RS15655 (I5961_15550)	3445002..3445948	+	947	Protein_3087	transporter	-
I5961_RS15660 (I5961_15555)	3446202..3446396	+	195	WP_085701856.1	stability determinant	Antitoxin
I5961_RS15665 (I5961_15560)	3446434..3446670	+	237	WP_234206646.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-129)

Antitoxin

• SpoVT-AbrB domain (7-52)

Sequences

Toxin

Protein

• Length: 79 a.a.
• Molecular weight: 8865.05 Da
• Isoelectric Point: 10.5558

>T182562 WP_234206646.1 NZ_CP065410:3446434-3446670 [Pseudomonas sp. IAC-BECa141]
IDYVEQYNSNASTALQHKVGAATQRLSSIPYGYRSGRVPGTREMVVNPNYLLVYRVNGHIKILTLVHTRRQYPRTSST

Nucleotide

• Length: 237 bp

>T182562 NZ_CP086492:77203-77619 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin

Protein

• Length: 65 a.a.
• Molecular weight: 7478.44 Da
• Isoelectric Point: 4.7815

>AT182562 WP_085701856.1 NZ_CP065410:3446202-3446396 [Pseudomonas sp. IAC-BECa141]
MSILLSPFYSDFESEEEAESYDRWFRAKVQAVLDDPRPGIPHKEAMVRLDQLLEEKRKNRPAAA

Nucleotide

• Length: 195 bp

>AT182562 NZ_CP086492:76976-77206 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA