Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2292654..2293134 Replicon chromosome
Accession NZ_CP065410
Organism Pseudomonas sp. IAC-BECa141

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I5961_RS10405 Protein ID WP_080770598.1
Coordinates 2292654..2292938 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I5961_RS10410 Protein ID WP_103387228.1
Coordinates 2292928..2293134 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5961_RS10365 (I5961_10335) 2288002..2288475 + 474 WP_007956136.1 type II secretion system protein -
I5961_RS10370 (I5961_10340) 2288481..2288855 + 375 WP_011333435.1 type II secretion system protein -
I5961_RS10375 (I5961_10345) 2288830..2289381 + 552 WP_085704853.1 type II secretion system protein -
I5961_RS10380 (I5961_10350) 2289378..2289770 + 393 WP_085698595.1 curli production assembly/transport protein CsgE -
I5961_RS10385 (I5961_10355) 2289767..2290198 + 432 WP_007956141.1 curli assembly protein CsgF -
I5961_RS10390 (I5961_10360) 2290228..2291088 + 861 WP_227235128.1 CsgG/HfaB family protein -
I5961_RS10395 (I5961_10365) 2291868..2292248 + 381 WP_227235130.1 DUF6124 family protein -
I5961_RS10400 (I5961_10370) 2292322..2292513 + 192 WP_085698598.1 antitoxin -
I5961_RS10405 (I5961_10375) 2292654..2292938 - 285 WP_080770598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I5961_RS10410 (I5961_10380) 2292928..2293134 - 207 WP_103387228.1 antitoxin Antitoxin
I5961_RS10415 (I5961_10385) 2293406..2294857 - 1452 WP_227235132.1 curlin -
I5961_RS10420 (I5961_10390) 2294884..2295348 - 465 WP_227235133.1 curlin -
I5961_RS10425 (I5961_10395) 2295442..2297676 - 2235 WP_227235135.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10918.75 Da        Isoelectric Point: 10.9931

>T182561 WP_080770598.1 NZ_CP065410:c2292938-2292654 [Pseudomonas sp. IAC-BECa141]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALPWHPHLYRKGRSPGTREIVVSPNYLVVYQVADRIEIVS
ILHARQEYPRRDPS

Download         Length: 285 bp

>T182561 NZ_CP086492:c76196-75891 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCTGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7556.46 Da        Isoelectric Point: 3.9012

>AT182561 WP_103387228.1 NZ_CP065410:c2293134-2292928 [Pseudomonas sp. IAC-BECa141]
MIDPSLIDPLCPVVSDLGPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMAEINALMESMRKSADAD

Download         Length: 207 bp

>AT182561 NZ_CP086492:c76416-76198 [Escherichia coli]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGGCT
GGTAAGCACCACCCTGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCAGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References