Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-StbC
Location 1639396..1640056 Replicon chromosome
Accession NZ_CP065403
Organism Paraburkholderia caribensis strain IAC-BECa88

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I5286_RS07190 Protein ID WP_082434037.1
Coordinates 1639628..1640056 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I5286_RS07185 Protein ID WP_035991398.1
Coordinates 1639396..1639641 (+) Length 82 a.a.

Genomic Context

I5286_RS07165I5286_RS07170I5286_RS07175I5286_RS07185I5286_RS07190I5286_RS07195I5286_RS07200I5286_RS07210I5286_RS07160I5286_RS07180I5286_RS07205
Location: 1635655..1636539 (885 bp)
Type: Others
Protein ID: WP_224102400.1
Location: 1636676..1637140 (465 bp)
Type: Others
Protein ID: WP_035990996.1
Location: 1637348..1638445 (1098 bp)
Type: Others
Protein ID: WP_035990998.1
Location: 1639396..1639641 (246 bp)
Type: Antitoxin
Protein ID: WP_035991398.1
Location: 1639628..1640056 (429 bp)
Type: Toxin
Protein ID: WP_082434037.1
Location: 1640145..1640618 (474 bp)
Type: Others
Protein ID: WP_227244091.1
Location: 1640823..1641800 (978 bp)
Type: Others
Protein ID: WP_054934556.1
Location: 1643032..1643988 (957 bp)
Type: Others
Protein ID: WP_227244094.1
Location: 1634990..1635502 (513 bp)
Type: Others
Protein ID: WP_035990992.1
Location: 1638606..1639226 (621 bp)
Type: Others
Protein ID: WP_227244089.1
Location: 1641843..1642481 (639 bp)
Type: Others
Protein ID: WP_227244092.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I5286_RS071601634990..1635502-513WP_035990992.1Spy/CpxP family protein refolding chaperone-
I5286_RS071651635655..1636539+885WP_224102400.1LysR family transcriptional regulator-
I5286_RS071701636676..1637140+465WP_035990996.1Lrp/AsnC family transcriptional regulator-
I5286_RS071751637348..1638445+1098WP_035990998.1saccharopine dehydrogenase C-terminal domain-containing protein-
I5286_RS071801638606..1639226-621WP_227244089.1ATP-binding protein-
I5286_RS071851639396..1639641+246WP_035991398.1DNA-binding proteinAntitoxin
I5286_RS071901639628..1640056+429WP_082434037.1type II toxin-antitoxin system VapC family toxinToxin
I5286_RS071951640145..1640618+474WP_227244091.1DUF2846 domain-containing protein-
I5286_RS072001640823..1641800+978WP_054934556.1magnesium/cobalt transporter CorA-
I5286_RS072051641843..1642481-639WP_227244092.1LysE family translocator-
I5286_RS072101643032..1643988+957WP_227244094.1sugar ABC transporter substrate-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15715.91 Da        Isoelectric Point: 7.4682

>T182547 WP_082434037.1 NZ_CP065403:1639628-1640056 [Paraburkholderia caribensis]
VYLIDTNVISEMRKSSRANPGVQAFFETAKEGGHRLYLSVVTVGELRRGVDLIRHRGDKFQALRLEGWLDTIMNSFSSHI
LNVGTDVAQTWGHLRVPDPGHSLDKLIAATALIYNLTVVTRNVADFDGTGARVLNPFQLLDA

Download         Length: 429 bp

>T182547 NZ_CP086490:2144416-2144519 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8938.90 Da        Isoelectric Point: 4.2208

>AT182547 WP_035991398.1 NZ_CP065403:1639396-1639641 [Paraburkholderia caribensis]
MANLLVRNLDDALVQNLREQAAAHGRSVEAEHREILAQALFQPRKLSFAELLMSMPDVGDDADFERRNDATDDSGGPGVF
D

Download         Length: 246 bp

>AT182547 NZ_CP086490:c2144557-2144286 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References