Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929427..1929572 Replicon chromosome
Accession NZ_CP065401
Organism Klebsiella pneumoniae strain KPNSP-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929463..1929565 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929427..1929572 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5G01_RS09330 1924557..1926617 + 2061 WP_004899137.1 oligopeptidase B -
I5G01_RS09335 1926621..1927280 - 660 WP_002911407.1 exodeoxyribonuclease X -
I5G01_RS09340 1927359..1927589 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5G01_RS09345 1927702..1928076 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I5G01_RS09350 1928080..1928949 + 870 WP_004899136.1 copper homeostasis membrane protein CopD -
I5G01_RS09355 1928966..1929304 + 339 WP_002911404.1 YebY family protein -
- 1929427..1929572 - 146 - - Antitoxin
- 1929463..1929565 + 103 - - Toxin
I5G01_RS09360 1929940..1930083 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I5G01_RS09365 1930188..1931156 - 969 WP_004151446.1 VirK/YbjX family protein -
I5G01_RS09370 1931313..1931966 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
I5G01_RS09375 1931963..1932154 - 192 WP_002911395.1 YebW family protein -
I5G01_RS09380 1932252..1932491 - 240 WP_002911393.1 YebV family protein -
I5G01_RS09385 1932607..1934040 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182530 NZ_CP065401:1929463-1929565 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182530 NZ_CP065401:c1929572-1929427 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References