Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2937474..2937943 Replicon chromosome
Accession NZ_CP065383
Organism Atribacter laminatus strain RT761

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RT761_RS13270 Protein ID WP_218111898.1
Coordinates 2937474..2937737 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag RT761_RS13275 Protein ID WP_218111899.1
Coordinates 2937734..2937943 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RT761_RS13250 (RT761_02652) 2933327..2933686 + 360 WP_218111894.1 TraR/DksA family transcriptional regulator -
RT761_RS13255 (RT761_02653) 2933738..2934187 - 450 WP_218111895.1 adenosylmethionine decarboxylase -
RT761_RS13260 (RT761_02654) 2935203..2936657 + 1455 WP_218111896.1 transposase -
RT761_RS13265 (RT761_02655) 2936709..2937290 + 582 WP_218111897.1 hypothetical protein -
RT761_RS13270 (RT761_02656) 2937474..2937737 - 264 WP_218111898.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RT761_RS13275 (RT761_02657) 2937734..2937943 - 210 WP_218111899.1 ribbon-helix-helix domain-containing protein Antitoxin
RT761_RS13285 (RT761_02658) 2939635..2939859 - 225 WP_218111901.1 type II toxin-antitoxin system HicA family toxin -
RT761_RS13290 (RT761_02659) 2939860..2940078 - 219 WP_218111902.1 type II toxin-antitoxin system HicB family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin

Protein of unknown function DUF6290

(1-66)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10410.39 Da        Isoelectric Point: 10.4247

>T182508 WP_218111898.1 NZ_CP065383:c2937737-2937474 [Atribacter laminatus]
MNYQILWHKDAVQDLKKIDRKIALSIISKVEKYLARDPIKLSMPLKGNFKGFFRYRIGKFRVIYTIQENHLLILVLKVGK
RDEVYDE

Download         Length: 264 bp

>T182508 NZ_CP086480:655570-655884 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 8228.36 Da        Isoelectric Point: 4.8279

>AT182508 WP_218111899.1 NZ_CP065383:c2937943-2937734 [Atribacter laminatus]
MISIRLPKDLEKKLDILAQSTKRSKSFYVKEALTRYLEDIEDYYVVLERFSQPGSDYYTTEEVKKEIES

Download         Length: 210 bp

>AT182508 NZ_CP086480:655881-656297 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References