Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 5116806..5117511 Replicon chromosome
Accession NZ_CP065358
Organism Kosakonia oryzae strain IAC-BECa90

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I5186_RS24410 Protein ID WP_227121965.1
Coordinates 5117125..5117511 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I5186_RS24405 Protein ID WP_064568757.1
Coordinates 5116806..5117132 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5186_RS24390 (I5186_24290) 5112455..5113150 + 696 WP_227123211.1 D-allulose 6-phosphate 3-epimerase -
I5186_RS24395 (I5186_24295) 5113134..5114081 + 948 WP_064568755.1 allose kinase -
I5186_RS24400 (I5186_24300) 5114035..5116599 - 2565 WP_227121964.1 ATP-binding protein -
I5186_RS24405 (I5186_24305) 5116806..5117132 - 327 WP_064568757.1 helix-turn-helix domain-containing protein Antitoxin
I5186_RS24410 (I5186_24310) 5117125..5117511 - 387 WP_227121965.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I5186_RS24415 (I5186_24315) 5117734..5119257 + 1524 WP_064568759.1 sugar ABC transporter ATP-binding protein -
I5186_RS24420 (I5186_24320) 5119250..5120239 + 990 WP_064568760.1 ribose ABC transporter permease -
I5186_RS24425 (I5186_24325) 5120280..5121221 + 942 WP_043955595.1 ABC transporter substrate-binding protein -
I5186_RS24430 (I5186_24330) 5121267..5121953 + 687 WP_227121966.1 D-lyxose/D-mannose family sugar isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-124)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-92)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13598.65 Da        Isoelectric Point: 9.6721

>T182488 WP_227121965.1 NZ_CP065358:c5117511-5117125 [Kosakonia oryzae]
MAIYVLKAFDKNTKGDGIDDAALCKAAQEAISGKYEASLGGGVFKKRIPLPGTGKSGGARAVIAFKMGKHLFFLNGYAKS
ATSSNGKEIPDDVLKAYRKFAADLFGMTQAQIDAQVQAETMREVKCDG

Download         Length: 387 bp

>T182488 NZ_CP086470:2755167-2755274 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12223.12 Da        Isoelectric Point: 6.7285

>AT182488 WP_064568757.1 NZ_CP065358:c5117132-5116806 [Kosakonia oryzae]
MVDHLKDLQEMAHDMFPHGGISEDTVNYIDARVKLRELRARLPAIVEMDGEAIRALRGRYNLSQAMLAEYVNMSVVTISK
WERGEKKPNGAALRVLNTLSDKGPEIFI

Download         Length: 327 bp

>AT182488 NZ_CP086470:c2755120-2755054 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References