Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4812010..4812526 Replicon chromosome
Accession NZ_CP065358
Organism Kosakonia oryzae strain IAC-BECa90

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I5186_RS22905 Protein ID WP_227121855.1
Coordinates 4812010..4812294 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I5186_RS22910 Protein ID WP_007372820.1
Coordinates 4812284..4812526 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5186_RS22890 (I5186_22790) 4807105..4808760 + 1656 WP_227121853.1 alpha,alpha-phosphotrehalase -
I5186_RS22895 (I5186_22795) 4809141..4811276 + 2136 WP_064568650.1 anaerobic ribonucleoside-triphosphate reductase -
I5186_RS22900 (I5186_22800) 4811539..4812003 + 465 WP_227121854.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
I5186_RS22905 (I5186_22805) 4812010..4812294 - 285 WP_227121855.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I5186_RS22910 (I5186_22810) 4812284..4812526 - 243 WP_007372820.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I5186_RS22915 (I5186_22815) 4812613..4813548 - 936 WP_227121856.1 AraC family transcriptional regulator -
I5186_RS22920 (I5186_22820) 4813658..4814491 + 834 WP_227121857.1 oxidoreductase -
I5186_RS22925 (I5186_22825) 4814528..4816438 - 1911 WP_227121858.1 PRD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11069.95 Da        Isoelectric Point: 10.3524

>T182487 WP_227121855.1 NZ_CP065358:c4812294-4812010 [Kosakonia oryzae]
MTYELVFDPRAYREWEKLGETVRAQFKKKLADVLVQPRIEAARPHDFPDCYKITLRPSGYRLIYQVCNNVVTVFVIAVGK
REKAAAYRHARKRL

Download         Length: 285 bp

>T182487 NZ_CP086470:c2542205-2542029 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9166.58 Da        Isoelectric Point: 4.6017

>AT182487 WP_007372820.1 NZ_CP065358:c4812526-4812284 [Kosakonia oryzae]
MATLNVRLDDNLKEEAWTVLEKLNITPTEAVRMLFQYVAENGRMPIKTVTVSDDEEALLKIVRERLANPQKGIRVNLDDL

Download         Length: 243 bp

>AT182487 NZ_CP086470:c2541983-2541567 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References