Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 4623150..4623724 Replicon chromosome
Accession NZ_CP065358
Organism Kosakonia oryzae strain IAC-BECa90

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I5186_RS21980 Protein ID WP_167351157.1
Coordinates 4623150..4623362 (-) Length 71 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I5186_RS21985 Protein ID WP_064568527.1
Coordinates 4623452..4623724 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5186_RS21955 (I5186_21860) 4619240..4619707 - 468 WP_227121764.1 YjiG family protein -
I5186_RS21960 (I5186_21865) 4619700..4620383 - 684 WP_064568523.1 nucleoside recognition domain-containing protein -
I5186_RS21965 (I5186_21870) 4620763..4621659 + 897 WP_064568524.1 LysR substrate-binding domain-containing protein -
I5186_RS21970 (I5186_21875) 4621704..4622468 + 765 WP_064568525.1 AraC family transcriptional regulator -
I5186_RS21975 (I5186_21880) 4622518..4623144 + 627 WP_064568526.1 LysE family translocator -
I5186_RS21980 (I5186_21885) 4623150..4623362 - 213 WP_167351157.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
I5186_RS21985 (I5186_21890) 4623452..4623724 - 273 WP_064568527.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I5186_RS21990 (I5186_21895) 4623810..4625090 + 1281 WP_064568528.1 DUF445 domain-containing protein -
I5186_RS21995 (I5186_21900) 4625178..4626329 + 1152 WP_064568529.1 double-cubane-cluster-containing anaerobic reductase -
I5186_RS22000 (I5186_21905) 4626339..4627103 + 765 WP_064568530.1 putative 2-hydroxyacyl-CoA dehydratase activator YjiL -
I5186_RS22005 (I5186_21910) 4627103..4627339 + 237 WP_227121765.1 DUF3343 domain-containing protein -
I5186_RS22010 (I5186_21915) 4627382..4628449 - 1068 WP_227121766.1 DUF2955 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(21-70)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-69)


Sequences

Toxin        


Download         Length: 71 a.a.        Molecular weight: 8328.54 Da        Isoelectric Point: 6.4730

>T182485 WP_167351157.1 NZ_CP065358:c4623362-4623150 [Kosakonia oryzae]
MRLRQLCRWYFLAARFPRNIAQYNDHALTGDMLGFRELHIGGDYLLVYRVDEDKHLVVFTDLGTHAELFE

Download         Length: 213 bp

>T182485 NZ_CP086470:2144416-2144519 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10085.40 Da        Isoelectric Point: 5.1584

>AT182485 WP_064568527.1 NZ_CP065358:c4623724-4623452 [Kosakonia oryzae]
MDSVIRSRIDSELKARAGLVLESCGLNWSTAIRLFAEQIVKNEGIPFEVTRKPTARLRNAMSEAEEITAHQHGRFEGVDQ
LMDSLNDGKE

Download         Length: 273 bp

>AT182485 NZ_CP086470:c2144557-2144286 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References