Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 860009..860672 Replicon chromosome
Accession NZ_CP065358
Organism Kosakonia oryzae strain IAC-BECa90

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag I5186_RS04235 Protein ID WP_227122349.1
Coordinates 860256..860672 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag I5186_RS04230 Protein ID WP_064563820.1
Coordinates 860009..860275 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5186_RS04210 (I5186_04200) 855454..856887 - 1434 WP_227122347.1 6-phospho-beta-glucosidase BglA -
I5186_RS04215 (I5186_04205) 857004..857732 - 729 WP_227123129.1 MurR/RpiR family transcriptional regulator -
I5186_RS04220 (I5186_04210) 858081..858740 + 660 WP_007370251.1 hemolysin III family protein -
I5186_RS04225 (I5186_04215) 858780..859760 - 981 WP_227122348.1 tRNA-modifying protein YgfZ -
I5186_RS04230 (I5186_04220) 860009..860275 + 267 WP_064563820.1 FAD assembly factor SdhE Antitoxin
I5186_RS04235 (I5186_04225) 860256..860672 + 417 WP_227122349.1 protein YgfX Toxin
I5186_RS04240 (I5186_04230) 860691..861212 - 522 WP_064563822.1 flavodoxin FldB -
I5186_RS04245 (I5186_04235) 861313..862209 + 897 WP_227122350.1 site-specific tyrosine recombinase XerD -
I5186_RS04250 (I5186_04240) 862234..862947 + 714 WP_227122351.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
I5186_RS04255 (I5186_04245) 862953..864686 + 1734 WP_227122352.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16300.22 Da        Isoelectric Point: 10.7373

>T182475 WP_227122349.1 NZ_CP065358:860256-860672 [Kosakonia oryzae]
VVLWQSELRVSWRAQWISLLLHGLGAALILLMPWPLSYTPLWLLLLSLVVFDCVRSQRRINACHGELKLLIDSRLRWQGV
EWDIIGTPWMLRSGMMLRLRREEDGRRQHLWLAADSMDAQEWRDLRRVISQKPAQGLH

Download         Length: 417 bp

>T182475 NZ_CP086470:185984-186091 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10456.88 Da        Isoelectric Point: 5.1069

>AT182475 WP_064563820.1 NZ_CP065358:860009-860275 [Kosakonia oryzae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQLFVRLLESDDPDLFNWLMNHGEPQDAGLQKMVRLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT182475 NZ_CP086470:c185936-185870 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References