Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1931027..1931172 | Replicon | chromosome |
| Accession | NZ_CP065351 | ||
| Organism | Klebsiella pneumoniae strain ZG2017CW4-3-1-2N | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1931063..1931165 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1931027..1931172 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I5Q74_RS09355 | 1926157..1928217 | + | 2061 | WP_047694778.1 | oligopeptidase B | - |
| I5Q74_RS09360 | 1928221..1928880 | - | 660 | WP_102000926.1 | exodeoxyribonuclease X | - |
| I5Q74_RS09365 | 1928959..1929189 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| I5Q74_RS09370 | 1929302..1929676 | + | 375 | WP_023285314.1 | CopC domain-containing protein YobA | - |
| I5Q74_RS09375 | 1929680..1930549 | + | 870 | WP_023285313.1 | copper homeostasis membrane protein CopD | - |
| I5Q74_RS09380 | 1930566..1930904 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1931027..1931172 | - | 146 | - | - | Antitoxin |
| - | 1931063..1931165 | + | 103 | - | - | Toxin |
| I5Q74_RS09385 | 1931540..1931683 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| I5Q74_RS09390 | 1931788..1932756 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| I5Q74_RS09395 | 1932913..1933566 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| I5Q74_RS09400 | 1933563..1933754 | - | 192 | WP_002911395.1 | YebW family protein | - |
| I5Q74_RS09405 | 1933852..1934091 | - | 240 | WP_002911393.1 | YebV family protein | - |
| I5Q74_RS09410 | 1934207..1935640 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T182428 NZ_CP065351:1931063-1931165 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT182428 NZ_CP065351:c1931172-1931027 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT