Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1931027..1931172 Replicon chromosome
Accession NZ_CP065351
Organism Klebsiella pneumoniae strain ZG2017CW4-3-1-2N

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1931063..1931165 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1931027..1931172 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5Q74_RS09355 1926157..1928217 + 2061 WP_047694778.1 oligopeptidase B -
I5Q74_RS09360 1928221..1928880 - 660 WP_102000926.1 exodeoxyribonuclease X -
I5Q74_RS09365 1928959..1929189 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5Q74_RS09370 1929302..1929676 + 375 WP_023285314.1 CopC domain-containing protein YobA -
I5Q74_RS09375 1929680..1930549 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
I5Q74_RS09380 1930566..1930904 + 339 WP_002911404.1 YebY family protein -
- 1931027..1931172 - 146 - - Antitoxin
- 1931063..1931165 + 103 - - Toxin
I5Q74_RS09385 1931540..1931683 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I5Q74_RS09390 1931788..1932756 - 969 WP_004151446.1 VirK/YbjX family protein -
I5Q74_RS09395 1932913..1933566 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
I5Q74_RS09400 1933563..1933754 - 192 WP_002911395.1 YebW family protein -
I5Q74_RS09405 1933852..1934091 - 240 WP_002911393.1 YebV family protein -
I5Q74_RS09410 1934207..1935640 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182428 NZ_CP065351:1931063-1931165 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182428 NZ_CP065351:c1931172-1931027 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References