Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1931029..1931174 Replicon chromosome
Accession NZ_CP065341
Organism Klebsiella pneumoniae strain ZG2017CW 1-1-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1931065..1931167 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1931029..1931174 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5Q76_RS09355 1926159..1928219 + 2061 WP_047694778.1 oligopeptidase B -
I5Q76_RS09360 1928223..1928882 - 660 WP_102000926.1 exodeoxyribonuclease X -
I5Q76_RS09365 1928961..1929191 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I5Q76_RS09370 1929304..1929678 + 375 WP_023285314.1 CopC domain-containing protein YobA -
I5Q76_RS09375 1929682..1930551 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
I5Q76_RS09380 1930568..1930906 + 339 WP_002911404.1 YebY family protein -
- 1931029..1931174 - 146 - - Antitoxin
- 1931065..1931167 + 103 - - Toxin
I5Q76_RS09385 1931542..1931685 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I5Q76_RS09390 1931790..1932758 - 969 WP_004151446.1 VirK/YbjX family protein -
I5Q76_RS09395 1932915..1933568 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
I5Q76_RS09400 1933565..1933756 - 192 WP_002911395.1 YebW family protein -
I5Q76_RS09405 1933854..1934093 - 240 WP_002911393.1 YebV family protein -
I5Q76_RS09410 1934209..1935642 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182372 NZ_CP065341:1931065-1931167 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182372 NZ_CP065341:c1931174-1931029 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References