Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4107579..4107747 Replicon chromosome
Accession NZ_CP065338
Organism Klebsiella michiganensis strain LDS17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4107637..4107740 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4107579..4107747 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I4W82_RS19220 (I4W82_19215) 4102706..4104766 + 2061 WP_033836507.1 oligopeptidase B -
I4W82_RS19225 (I4W82_19220) 4104773..4105432 - 660 WP_014229839.1 exodeoxyribonuclease X -
I4W82_RS19230 (I4W82_19225) 4105511..4105741 - 231 WP_004103351.1 DNA polymerase III subunit theta -
I4W82_RS19235 (I4W82_19230) 4105877..4106251 + 375 WP_014229838.1 CopC domain-containing protein YobA -
I4W82_RS19240 (I4W82_19235) 4106256..4107125 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
I4W82_RS19245 (I4W82_19240) 4107142..4107480 + 339 WP_004103344.1 YebY family protein -
- 4107579..4107747 - 169 - - Antitoxin
- 4107637..4107740 + 104 - - Toxin
I4W82_RS19250 (I4W82_19245) 4107865..4108824 - 960 WP_047723552.1 spore coat protein U domain-containing protein -
I4W82_RS19255 (I4W82_19250) 4108839..4111169 - 2331 WP_209419845.1 fimbria/pilus outer membrane usher protein -
I4W82_RS19260 (I4W82_19255) 4111172..4111936 - 765 WP_134897814.1 fimbria/pilus periplasmic chaperone -
I4W82_RS19265 (I4W82_19260) 4111955..4112473 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T182360 NZ_CP065338:4107637-4107740 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT182360 NZ_CP065338:c4107747-4107579 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References