Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-ArgA
Location 809451..810270 Replicon chromosome
Accession NZ_CP065338
Organism Klebsiella michiganensis strain LDS17

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag I4W82_RS03780 Protein ID WP_209420152.1
Coordinates 810013..810270 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag I4W82_RS03775 Protein ID WP_154970970.1
Coordinates 809451..810002 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I4W82_RS03760 (I4W82_03760) 804821..806218 + 1398 WP_014228060.1 MFS transporter -
I4W82_RS03765 (I4W82_03765) 806340..807680 + 1341 WP_163586119.1 carbohydrate porin -
I4W82_RS27055 807805..808551 - 747 WP_224322392.1 class I SAM-dependent methyltransferase -
I4W82_RS27060 808978..809337 - 360 Protein_739 class I SAM-dependent methyltransferase -
I4W82_RS03775 (I4W82_03775) 809451..810002 - 552 WP_154970970.1 N-acetyltransferase Antitoxin
I4W82_RS03780 (I4W82_03780) 810013..810270 - 258 WP_209420152.1 YjhX family toxin Toxin
I4W82_RS03785 (I4W82_03785) 810946..812130 + 1185 WP_047724369.1 mannonate dehydratase -
I4W82_RS03790 (I4W82_03790) 812204..813679 + 1476 WP_209420153.1 fructuronate reductase -
I4W82_RS03795 (I4W82_03795) 813816..814592 + 777 WP_209420154.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9578.10 Da        Isoelectric Point: 10.9564

>T182355 WP_209420152.1 NZ_CP065338:c810270-810013 [Klebsiella michiganensis]
MNLSRQEQRTLHVLAKGGRIAYIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

>T182355 NZ_CP086417:c14266-13916 [Klebsiella pneumoniae]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 19932.66 Da        Isoelectric Point: 6.4913

>AT182355 WP_154970970.1 NZ_CP065338:c810002-809451 [Klebsiella michiganensis]
MTNHSFTFHVASEGDTDDILDVETRAFGYSKEARLVADLLNDESACPTLSLLARHNGEAVGHILFTRATFKGEPDSPMMH
ILAPLTVVPEYQGAGVGGELIRHGIEQLKAMGSQAVFVLGHAAYYPRHGFEPGAGDKGYPAPYPIPAAHKACWMLQPISS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp

>AT182355 NZ_CP086417:c13911-13609 [Klebsiella pneumoniae]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References