182330

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 3546863..3547373 Replicon chromosome
Accession NZ_CP065230
Organism Halomonas sp. A40-4

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag IT895_RS16530 Protein ID WP_199284085.1
Coordinates 3547110..3547373 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IT895_RS16525 Protein ID WP_199284084.1
Coordinates 3546863..3547117 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IT895_RS16505 3542999..3543622 + 624 WP_085919763.1 TetR family transcriptional regulator -
IT895_RS16510 3543690..3544955 + 1266 WP_199284081.1 cytosine permease -
IT895_RS16515 3544973..3546241 + 1269 WP_199284082.1 cytosine deaminase -
IT895_RS16520 3546293..3546769 + 477 WP_199284083.1 YbaK/EbsC family protein -
IT895_RS16525 3546863..3547117 + 255 WP_199284084.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IT895_RS16530 3547110..3547373 + 264 WP_199284085.1 Txe/YoeB family addiction module toxin Toxin
IT895_RS16535 3547375..3547830 - 456 WP_199284086.1 rhodanese -
IT895_RS16540 3547841..3548290 - 450 WP_199284087.1 GNAT family N-acetyltransferase -
IT895_RS16545 3548383..3549873 + 1491 WP_199284088.1 PLP-dependent aminotransferase family protein -
IT895_RS16550 3550080..3550745 + 666 WP_085919759.1 CDP-alcohol phosphatidyltransferase family protein -
IT895_RS16555 3550756..3551385 + 630 WP_199284089.1 DNA-3-methyladenine glycosylase I -
IT895_RS16560 3551453..3552004 - 552 WP_085919757.1 fasciclin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10304.71 Da        Isoelectric Point: 9.0362

>T182330 WP_199284085.1 NZ_CP065230:3547110-3547373 [Halomonas sp. A40-4]
MNSRLLCWTNEAWSDYLYWQGQDKKTLKRINKLISDTQRSPFEGIGKPEPLRENLSGLWSRRIDDTHRLVYAVDASTLTI
IACRYHY

Download         Length: 264 bp

>T182330 NZ_CP086409:98975-99286 [Enterobacter cloacae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTGAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9472.66 Da        Isoelectric Point: 4.5408

>AT182330 WP_199284084.1 NZ_CP065230:3546863-3547117 [Halomonas sp. A40-4]
MRVISFTEARNGLKSLLDGVVNDADTTIITRRDAEDAVVMSLDYYNSLMETVYLMRSPANAERLNKSIAQYRAGQAQSRE
LIDE

Download         Length: 255 bp

>AT182330 NZ_CP086409:99283-99702 [Enterobacter cloacae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References