Detailed information of TA system TA182327

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 4257373..4257929
• Replicon: chromosome
• Accession: NZ_CP065228
• Organism: Xanthomonas oryzae pv. oryzae strain BXO512

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BXO512_RS19840
• Protein ID: WP_229001948.1
• Coordinates: 4257678..4257929 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BXO512_RS19835
• Protein ID: WP_011408759.1
• Coordinates: 4257373..4257651 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXO512_RS19815 (BXO512_019790)	4252490..4253047	-	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-
BXO512_RS19820 (BXO512_019795)	4253197..4254162	-	966	WP_109181970.1	IS1595-like element ISXo5 family transposase	-
BXO512_RS19825 (BXO512_019800)	4254743..4255927	+	1185	WP_117231633.1	IS256 family transposase	-
BXO512_RS19830 (BXO512_019810)	4256833..4257177	+	345	WP_198912817.1	hypothetical protein	-
BXO512_RS19835 (BXO512_019815)	4257373..4257651	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BXO512_RS19840 (BXO512_019820)	4257678..4257929	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BXO512_RS19845 (BXO512_019825)	4258190..4258387	+	198	WP_004541336.1	hypothetical protein	-
BXO512_RS19850 (BXO512_019830)	4258456..4258710	+	255	WP_223293127.1	hypothetical protein	-
BXO512_RS19855	4258927..4259046	+	120	Protein_3803	IS3 family transposase	-
BXO512_RS23080	4259015..4259143	+	129	WP_012444694.1	hypothetical protein	-
BXO512_RS19865 (BXO512_019845)	4259574..4259975	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
BXO512_RS19870 (BXO512_019850)	4260197..4260373	+	177	Protein_3806	DUF3606 domain-containing protein	-
BXO512_RS19875 (BXO512_019860)	4260655..4260992	+	338	Protein_3807	ATP-dependent DNA ligase	-
BXO512_RS19880 (BXO512_019865)	4261068..4262159	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T182327 WP_229001948.1 NZ_CP065228:4257678-4257929 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T182327 NZ_CP086408:4066742-4067119 [Enterobacter cloacae]
ATGAAAACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTGTC
CCGGTTGCTGGACCAGCATTACGGCCTTACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATTCTCCGGGCTCGCAGGGCAACCGGCCTGATGACCCGCGA
TAACTACAGAACGGTAAATAACATTACCCAGGGGAAGCATCCGGAGGCGAAACAATGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT182327 WP_011408759.1 NZ_CP065228:4257373-4257651 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT182327 NZ_CP086408:4066326-4066652 [Enterobacter cloacae]
ATGAGCAACCCTACCAGGGGCCTGCAGCGGGAGATTACACTGCGCCTGGGAGCCCGTCTGGTGCAGGAAGGCAACCGACT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGCAAGTTCAGTGACATCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCGCCAGATGGAATCGATGCTGACCACCGGTGAACTCAGCCCCCACCATGCCCACTGCGTTACCCTGTACCAC
AACGATTTAACCTGCGAAGCCGACACCTTCGGCTCCTGTGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAA
AAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2