Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3741983..3743502 Replicon chromosome
Accession NZ_CP065228
Organism Xanthomonas oryzae pv. oryzae strain BXO512

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag BXO512_RS17600 Protein ID WP_011259680.1
Coordinates 3742579..3743502 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag BXO512_RS17595 Protein ID WP_011409027.1
Coordinates 3741983..3742582 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXO512_RS17555 (BXO512_017495) 3737651..3738187 - 537 WP_024743012.1 lipocalin family protein -
BXO512_RS17565 3738564..3738938 - 375 WP_237384745.1 hypothetical protein -
BXO512_RS17570 3738919..3739209 - 291 WP_011409031.1 hypothetical protein -
BXO512_RS17580 (BXO512_017515) 3739708..3740739 + 1032 WP_117231631.1 IS630 family transposase -
BXO512_RS17585 (BXO512_017520) 3740721..3741296 - 576 WP_080493559.1 BrxE family protein -
BXO512_RS17590 (BXO512_017525) 3741328..3741618 - 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
BXO512_RS17595 (BXO512_017530) 3741983..3742582 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
BXO512_RS17600 (BXO512_017535) 3742579..3743502 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BXO512_RS17605 3743582..3744052 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
BXO512_RS17610 (BXO512_017550) 3744518..3744760 + 243 WP_011259679.1 hypothetical protein -
BXO512_RS17615 (BXO512_017555) 3745185..3745694 + 510 WP_011259678.1 hypothetical protein -
BXO512_RS17620 (BXO512_017560) 3745711..3746243 - 533 Protein_3370 methyltransferase domain-containing protein -
BXO512_RS17625 (BXO512_017565) 3746263..3747639 - 1377 Protein_3371 IS5 family transposase -
BXO512_RS17630 (BXO512_017570) 3747751..3747903 - 153 Protein_3372 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3739765..3740739 974


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T182326 WP_011259680.1 NZ_CP065228:3742579-3743502 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T182326 NZ_CP086408:c3962008-3961595 [Enterobacter cloacae]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTATTGCTCCACGGCCTGGTCGCGGC
ATTTGTTTTACTGATGCCGTGGCCGCTTAGCTATACGCCGCTGTGGCTGTTGTTGCTGTCGTTCGTCGTTTTTGACAGCG
TGCGCAGCCAGCGCCGGATCAATGCCCGCCAGGGTGAGATCAAATTACTGATGGACTCCCGCCTGCGCTGGCAGGGTAAA
GAGTGGGATATCCTCGGTATGCCCTGGATGCTCAGTTCCGGCATGATGCTACGGTTACGCCAGGTGGGCGGCGGTAAGTG
CCAGCATCTGTGGCTGGCCGCCGACAGTATGGATATTGCGGAGTGGCGGGAACTGCGCCGGATGCTACTGCAGCAGCAAC
CGACGCAGGAATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT182326 WP_011409027.1 NZ_CP065228:3741983-3742582 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT182326 NZ_CP086408:c3962255-3961989 [Enterobacter cloacae]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCATGCCGACGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGAGGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References