182325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2623551..2623901 Replicon chromosome
Accession NZ_CP065228
Organism Xanthomonas oryzae pv. oryzae strain BXO512

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag BXO512_RS12245 Protein ID WP_011257368.1
Coordinates 2623767..2623901 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag BXO512_RS12240 Protein ID WP_011407410.1
Coordinates 2623551..2623703 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXO512_RS12215 (BXO512_012130) 2619822..2620505 - 684 WP_011257363.1 dTMP kinase -
BXO512_RS12220 2620985..2621527 - 543 Protein_2342 GTPase -
BXO512_RS12225 (BXO512_012145) 2621524..2621988 - 465 Protein_2343 hypothetical protein -
BXO512_RS12230 2621980..2622198 - 219 Protein_2344 hypothetical protein -
BXO512_RS12235 (BXO512_012150) 2622520..2623443 + 924 WP_011407409.1 arginase -
BXO512_RS12240 (BXO512_012155) 2623551..2623703 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
BXO512_RS12245 (BXO512_012160) 2623767..2623901 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
BXO512_RS12250 (BXO512_012165) 2624145..2624354 + 210 WP_011407411.1 CsbD family protein -
BXO512_RS12255 (BXO512_012170) 2624523..2625812 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
BXO512_RS12260 (BXO512_012175) 2625943..2626887 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T182325 WP_011257368.1 NZ_CP065228:2623767-2623901 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T182325 NZ_CP086408:c3117441-3117067 [Enterobacter cloacae]
GTGTGGACAATTATTACGACGGACAGGTTCGATTGCTGGTTTCGTTCACTTGATGATACTGATCGGGCCAGCGTGCTGGC
AGCACTGCTTGTTTTGCGAGAAAAGGGGCCTGCTTTGTCGAGGCCCTATGCCGATACGCTTAAAGGCTCTCGTCACAGCA
ACATGAAAGAGCTGCGCATTCAGAGTAAGGGCGATCCGTTGCGGGCATTTTTCGCGTTTGACCCAAACCGTACCGGCATT
GTGCTCTGTGCCGGCAATAAGGTCGGCAACGAAAGACGCTTTTACGATGAAATGCTTCTGGTGGCCGACCGGGAATTCAC
TCACTGGTTGAATACATTAAAAGAGAGGACGTTACGCGATGGGCAGAAACCTTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT182325 WP_011407410.1 NZ_CP065228:2623551-2623703 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT182325 NZ_CP086408:c3117083-3116781 [Enterobacter cloacae]
ATGGGCAGAAACCTTGAGCAGCTTATAGCGGATGAAAAATCGGATGTTGTTGCCAGCGCTCAGGCAATGGCTGCCGACAT
TTTGCTTAATATCCATCTGGCAGAGCTACGTGAAAAGGTGCAAAAAACGCAGGTTGAAATGGCGCAGGCGCTGGGCATCC
GACAGCCCACCGTCGCGGTCATGGAAAAGCCCGGGCGCGATCTGAAACTCTCTTCACTCAAGCGCTACGTTGAGGCTGCG
GGTGGAAAGCTTACGCTTGACGTTGAGTTACCGGATGGTTCGCATTATGAGTTTGTGCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References