Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/ParE-YefM |
| Location | 14664..15226 | Replicon | plasmid p-ED653 |
| Accession | NZ_CP065208 | ||
| Organism | Vibrio cyclitrophicus strain ED653 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | ITG08_RS22830 | Protein ID | WP_102277806.1 |
| Coordinates | 14664..14966 (-) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | - |
| Locus tag | ITG08_RS22835 | Protein ID | WP_102277808.1 |
| Coordinates | 14966..15226 (-) | Length | 87 a.a. |
Genomic Context
Location: 11976..13001 (1026 bp)
Type: Others
Protein ID: WP_102277803.1
Type: Others
Protein ID: WP_102277803.1
Location: 12998..13912 (915 bp)
Type: Others
Protein ID: WP_102277804.1
Type: Others
Protein ID: WP_102277804.1
Location: 14049..14660 (612 bp)
Type: Others
Protein ID: WP_102277805.1
Type: Others
Protein ID: WP_102277805.1
Location: 15444..15992 (549 bp)
Type: Others
Protein ID: WP_102277784.1
Type: Others
Protein ID: WP_102277784.1
Location: 16045..17421 (1377 bp)
Type: Others
Protein ID: WP_102277785.1
Type: Others
Protein ID: WP_102277785.1
Location: 17423..18118 (696 bp)
Type: Others
Protein ID: WP_102277786.1
Type: Others
Protein ID: WP_102277786.1
Location: 9840..10562 (723 bp)
Type: Others
Protein ID: WP_029203609.1
Type: Others
Protein ID: WP_029203609.1
Location: 14664..14966 (303 bp)
Type: Toxin
Protein ID: WP_102277806.1
Type: Toxin
Protein ID: WP_102277806.1
Location: 14966..15226 (261 bp)
Type: Antitoxin
Protein ID: WP_102277808.1
Type: Antitoxin
Protein ID: WP_102277808.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ITG08_RS22810 (ITG08_22760) | 9840..10562 | - | 723 | WP_029203609.1 | hypothetical protein | - |
| ITG08_RS22815 (ITG08_22765) | 11976..13001 | + | 1026 | WP_102277803.1 | DNA mismatch repair protein | - |
| ITG08_RS22820 (ITG08_22770) | 12998..13912 | + | 915 | WP_102277804.1 | AAA family ATPase | - |
| ITG08_RS22825 (ITG08_22775) | 14049..14660 | + | 612 | WP_102277805.1 | recombinase family protein | - |
| ITG08_RS22830 (ITG08_22780) | 14664..14966 | - | 303 | WP_102277806.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| ITG08_RS22835 (ITG08_22785) | 14966..15226 | - | 261 | WP_102277808.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| ITG08_RS22840 (ITG08_22790) | 15444..15992 | + | 549 | WP_102277784.1 | recombinase family protein | - |
| ITG08_RS22845 (ITG08_22795) | 16045..17421 | + | 1377 | WP_102277785.1 | hypothetical protein | - |
| ITG08_RS22850 (ITG08_22800) | 17423..18118 | + | 696 | WP_102277786.1 | class I SAM-dependent methyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..30774 | 30774 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11695.45 Da Isoelectric Point: 9.6605
>T182316 WP_102277806.1 NZ_CP065208:c14966-14664 [Vibrio cyclitrophicus]
MTHYKLSSAAQSDLIEIRRYTLERWGQTQWTTYFSELKQSMELLANNQLLGIGVSELGQNYFRFPLKHHVIYYIQKQEHI
VIAAVLGKHMSPAKHFSQLS
MTHYKLSSAAQSDLIEIRRYTLERWGQTQWTTYFSELKQSMELLANNQLLGIGVSELGQNYFRFPLKHHVIYYIQKQEHI
VIAAVLGKHMSPAKHFSQLS
Download Length: 303 bp
>T182316 NZ_CP086406:c25904-25419 [Enterobacter roggenkampii]
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA
GTGGGACGTGTAACAGCACCAGAACCATTATCCAGCTCCCATCAACTAGCAGAGTTCGTCAGTGGTGAGGCAGTACTTGA
TGACTGGCTTAAACAGAGGGGATTAAAAAACCAAGCTCTTGGTGCAGCACGAACGTTCGTCGTTTGTAAAAGAGACACTA
AACAGGTTGTCGGTTTTTACTCTCTGGCCACCGGCAGCGTTAACCACGTGGAAGCAATGGGAAGCCTCAGGCGCAATATG
CCAGATCCAATTCCCGTAATCATACTTGCTCGCCTGGCAGTTGATGTTTCATACCGTGGCCAAGGGCTCGGGGCCGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTCCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAACTTTTATCTTCACCATGGCTTTAAGGCATCACAAACTCAGGAACGGACATTGTTTTTAAAGTTACCA
CAGTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9616.96 Da Isoelectric Point: 4.1963
>AT182316 WP_102277808.1 NZ_CP065208:c15226-14966 [Vibrio cyclitrophicus]
MQSLTANTAKTKFGDLLMKVQREPVQINKNGSPVAVMMSCEEYEQLEALKLMVVKSRFEQAEADVLSDNLVDGDDFMNAL
DQGKFD
MQSLTANTAKTKFGDLLMKVQREPVQINKNGSPVAVMMSCEEYEQLEALKLMVVKSRFEQAEADVLSDNLVDGDDFMNAL
DQGKFD
Download Length: 261 bp
>AT182316 NZ_CP086406:c26158-25892 [Enterobacter roggenkampii]
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAAGAATCTCAAAGAGCACTTATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACGGACTTCATCCTGGAAATGGCATGTCAGGCTGCGGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCGGTTTCGGATGAGGCGGCTATTGATAAACTTCTG
GCAAGGAAACCTCAGTGGGACGTGTAA