Detailed information of TA system TA182283

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hipBA/HipA-HipB
• Location: 4315750..4316308
• Replicon: chromosome
• Accession: NZ_CP065178
• Organism: Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)

• Gene name: hipA
• Uniprot ID: -
• Locus tag: IG605_RS19855
• Protein ID: WP_226373283.1
• Coordinates: 4316057..4316308 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: hipB
• Uniprot ID: -
• Locus tag: IG605_RS19850
• Protein ID: WP_103943261.1
• Coordinates: 4315750..4316019 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IG605_RS19825 (IG605_019760)	4311272..4311823	+	552	WP_193401375.1	TetR/AcrR family transcriptional regulator	-
IG605_RS19830 (IG605_019765)	4311854..4312264	-	411	WP_193397266.1	helix-turn-helix domain-containing protein	-
IG605_RS19835 (IG605_019770)	4312379..4313230	+	852	WP_193407545.1	SDR family oxidoreductase	-
IG605_RS19840 (IG605_019775)	4313324..4314208	-	885	WP_193397264.1	LysR substrate-binding domain-containing protein	-
IG605_RS19845 (IG605_019780)	4314421..4315557	+	1137	WP_193407546.1	alpha/beta hydrolase	-
IG605_RS19850 (IG605_019785)	4315750..4316019	+	270	WP_103943261.1	helix-turn-helix domain-containing protein	Antitoxin
IG605_RS19855	4316057..4316308	+	252	WP_226373283.1	hypothetical protein	Toxin
IG605_RS19860	4316318..4316674	+	357	WP_226373284.1	HipA domain-containing protein	-
IG605_RS19865 (IG605_019800)	4316726..4317088	+	363	Protein_3866	RhuM family protein	-
IG605_RS19870 (IG605_019805)	4317148..4318512	-	1365	WP_180787248.1	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	-
IG605_RS19875 (IG605_019810)	4318641..4320275	-	1635	WP_180787247.1	membrane protein insertase YidC	-
IG605_RS19880 (IG605_019815)	4320278..4320535	-	258	WP_010281237.1	membrane protein insertion efficiency factor YidD	-
IG605_RS19885 (IG605_019820)	4320499..4320858	-	360	WP_010281235.1	ribonuclease P protein component	-
IG605_RS19890 (IG605_019825)	4320877..4321017	-	141	WP_005976668.1	50S ribosomal protein L34	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-66)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9381.72 Da
• Isoelectric Point: 4.7440

>T182283 WP_226373283.1 NZ_CP065178:4316057-4316308 [Pectobacterium quasiaquaticum]
VHDIKKIEYKTLSEQQLENILTGYLSDAPLSMIDTEDDFRISIAGAQEKTALLYLDDRWCLPLNATPTTHIIKLPIGKIE
SHS

Nucleotide

• Length: 252 bp

>T182283 NZ_CP086388:c63514-63098 [Escherichia coli]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCTGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGTGCCACCGGCC
CGAAGGCCTCGCCGCGCCACGTCCAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGACCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTGCCGGATCTGGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10062.40 Da
• Isoelectric Point: 9.7281

>AT182283 WP_103943261.1 NZ_CP065178:4315750-4316019 [Pectobacterium quasiaquaticum]
MMKITNSKQLSSYLKDVRITQKLSQGKVASKVGIRQDTVSSFEQHPDSTKLETFFKILSALNLELTVTPRNVDTTNNEAS
VASSWKEEW

Nucleotide

• Length: 270 bp

>AT182283 NZ_CP086388:c63741-63511 [Escherichia coli]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA