Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | sdenTA/AbiEii(toxin) |
| Location | 4103178..4104618 | Replicon | chromosome |
| Accession | NZ_CP065178 | ||
| Organism | Pectobacterium quasiaquaticum strain A398-S21-F17 | ||
Toxin (Protein)
| Gene name | sdenT | Uniprot ID | - |
| Locus tag | IG605_RS18840 | Protein ID | WP_193399053.1 |
| Coordinates | 4103178..4104065 (-) | Length | 296 a.a. |
Antitoxin (Protein)
| Gene name | sdenA | Uniprot ID | - |
| Locus tag | IG605_RS18845 | Protein ID | WP_193399052.1 |
| Coordinates | 4104094..4104618 (-) | Length | 175 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IG605_RS18815 (IG605_018750) | 4098694..4099602 | + | 909 | WP_193400275.1 | LysR family transcriptional regulator | - |
| IG605_RS18820 (IG605_018755) | 4099701..4100564 | + | 864 | WP_102117032.1 | YicC/YloC family endoribonuclease | - |
| IG605_RS18825 (IG605_018760) | 4100819..4101073 | - | 255 | Protein_3664 | IS1-like element transposase | - |
| IG605_RS18830 (IG605_018765) | 4101126..4102481 | - | 1356 | WP_193399054.1 | type II toxin-antitoxin system HipA family toxin | - |
| IG605_RS18835 (IG605_018770) | 4102471..4102761 | - | 291 | WP_180785889.1 | helix-turn-helix transcriptional regulator | - |
| IG605_RS18840 (IG605_018775) | 4103178..4104065 | - | 888 | WP_193399053.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IG605_RS18845 (IG605_018780) | 4104094..4104618 | - | 525 | WP_193399052.1 | hypothetical protein | Antitoxin |
| IG605_RS18850 (IG605_018785) | 4104763..4105515 | - | 753 | WP_226373219.1 | hypothetical protein | - |
| IG605_RS18855 (IG605_018790) | 4105768..4106787 | - | 1020 | WP_193399051.1 | SEC-C domain-containing protein | - |
| IG605_RS18860 (IG605_018795) | 4106909..4107202 | - | 294 | WP_193400968.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 4101126..4116443 | 15317 | |
| - | flank | IS/Tn | - | - | 4100771..4101073 | 302 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 296 a.a. Molecular weight: 34231.20 Da Isoelectric Point: 6.1730
>T182281 WP_193399053.1 NZ_CP065178:c4104065-4103178 [Pectobacterium quasiaquaticum]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMSQDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMSQDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG
Download Length: 888 bp
>T182281 NZ_CP086388:3302-3613 [Escherichia coli]
ATGCACGTTGTATCGAGAGCACCTTTCGATACAGCCACCAGGCAATTCCCCAATCAGGCAGCGGCACTAGACGACGTATA
CCGGACTTTGAAGAGAGAGAACTACACTTCACCGGACGAAATGAAAAAACGATTTGCCTCGCTGGACAGAATGAAATATC
GGGAGAAGTGGTGGGTGATCGATGTTGGCGGTGGGAATTTAAGGGTGATGTTTTTTGCTGATTTTGAACGTGGGAAAATC
TTTATAAAGCACATAACCACACACGCCGAATACGACAAGCTGACAGATTTTTACCGGAGAACTAAAGAATGA
ATGCACGTTGTATCGAGAGCACCTTTCGATACAGCCACCAGGCAATTCCCCAATCAGGCAGCGGCACTAGACGACGTATA
CCGGACTTTGAAGAGAGAGAACTACACTTCACCGGACGAAATGAAAAAACGATTTGCCTCGCTGGACAGAATGAAATATC
GGGAGAAGTGGTGGGTGATCGATGTTGGCGGTGGGAATTTAAGGGTGATGTTTTTTGCTGATTTTGAACGTGGGAAAATC
TTTATAAAGCACATAACCACACACGCCGAATACGACAAGCTGACAGATTTTTACCGGAGAACTAAAGAATGA
Antitoxin
Download Length: 175 a.a. Molecular weight: 19460.53 Da Isoelectric Point: 9.0551
>AT182281 WP_193399052.1 NZ_CP065178:c4104618-4104094 [Pectobacterium quasiaquaticum]
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKRGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKRGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES
Download Length: 525 bp
>AT182281 NZ_CP086388:3610-4029 [Escherichia coli]
ATGATGTACACCGATGCTATCCAGGCGGCAAACAGCCTGGTTAGCATTGTCCCCCTCCTGGGGGGCAATGCCTCTCGCAA
GGACTATGAAGACGCGCTGACGCTGGTTGAATACCTGGTTGAACACGAGCCAGATCATCCGCTGGTGGACATGCTGGTTG
CGAAAATTGCCCAGTATGAAGATGAGGCGGAAGAGTTCGCAGAGTTCAACGACCGTATTGCAGCGTTACCAAGTGGCGTG
GCCCTGCTGCGTGTCCTGATGGACCAGCACAAACTGACTCAGAGTGATTTTGAGGAAGAGATTGGTAAGAAATCGCTGGT
GAGCCGCATCCTTAACGGGACTCGCTCACTAACACTAGATCACATGAAAGCACTTGCGCGGCGCTTCAACATTCCGCCCA
GCTCATTCATGGACGCGTAA
ATGATGTACACCGATGCTATCCAGGCGGCAAACAGCCTGGTTAGCATTGTCCCCCTCCTGGGGGGCAATGCCTCTCGCAA
GGACTATGAAGACGCGCTGACGCTGGTTGAATACCTGGTTGAACACGAGCCAGATCATCCGCTGGTGGACATGCTGGTTG
CGAAAATTGCCCAGTATGAAGATGAGGCGGAAGAGTTCGCAGAGTTCAACGACCGTATTGCAGCGTTACCAAGTGGCGTG
GCCCTGCTGCGTGTCCTGATGGACCAGCACAAACTGACTCAGAGTGATTTTGAGGAAGAGATTGGTAAGAAATCGCTGGT
GAGCCGCATCCTTAACGGGACTCGCTCACTAACACTAGATCACATGAAAGCACTTGCGCGGCGCTTCAACATTCCGCCCA
GCTCATTCATGGACGCGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|