Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3460055..3460695 Replicon chromosome
Accession NZ_CP065178
Organism Pectobacterium quasiaquaticum strain A398-S21-F17

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag IG605_RS15910 Protein ID WP_102117298.1
Coordinates 3460055..3460471 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag IG605_RS15915 Protein ID WP_102117299.1
Coordinates 3460468..3460695 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG605_RS15890 (IG605_015835) 3456139..3457473 + 1335 WP_193407238.1 type I-F CRISPR-associated protein Csy1 -
IG605_RS15895 (IG605_015840) 3457470..3458402 + 933 WP_193407236.1 type I-F CRISPR-associated protein Csy2 -
IG605_RS15900 (IG605_015845) 3458416..3459429 + 1014 WP_102117296.1 type I-F CRISPR-associated protein Csy3 -
IG605_RS15905 (IG605_015850) 3459439..3459993 + 555 WP_102117297.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
IG605_RS15910 (IG605_015855) 3460055..3460471 - 417 WP_102117298.1 type II toxin-antitoxin system VapC family toxin Toxin
IG605_RS15915 (IG605_015860) 3460468..3460695 - 228 WP_102117299.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
IG605_RS15920 (IG605_015865) 3461546..3461965 - 420 WP_116155442.1 secondary thiamine-phosphate synthase enzyme YjbQ -
IG605_RS15925 (IG605_015870) 3461981..3464815 - 2835 WP_116186272.1 excinuclease ABC subunit UvrA -
IG605_RS15930 (IG605_015875) 3465066..3465623 + 558 WP_116155441.1 single-stranded DNA-binding protein SSB1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-130)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15073.62 Da        Isoelectric Point: 9.3444

>T182279 WP_102117298.1 NZ_CP065178:c3460471-3460055 [Pectobacterium quasiaquaticum]
VSRLFMLDTNICSFIMREHPAAVIEKLQQCTLRRDRIVVSAITYAEMRFGAVGKKASPRHMPLVDAFCRRLDAVLPWDSA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVAGLTLEDWAK

Download         Length: 417 bp

>T182279 NZ_CP086385:9411-9812 [Deinococcus radiophilus]
GTGAGCCTCACCCACCTGCTGGACACCAACACCTGCATCTACATCTTAGGCCGCCGACCGCCTCACGTGGCCGAGCGGTT
TGCCGAGCATCCAGCCGACGCCATCGGGCTATCAAGCATCACCCTCGCGGAGCTGCGGTATGGCGTGAGCAAAAGCGGGT
CGGTCAGGAACGCGGCTGTGCTGGAGGCGTTCGTCGAGCCGCTGGAAGTATTGCCTTTTGGCGCAGAGGCCACCGAGCAT
TACGGCGCGCTGCGGGCGGCGCTGGAAGCGGGTGGGCGTCCCATTGGCGCGATGGACCTTCTCATTGCAGCCCACGCCCT
TTCCCTCGGGGCAACGCTGGTGACCAACAACGTCAAAGAGTTTGAGCGCGTCCCTGACCTGCGATTGGAGAACTGGTTTT
GA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8871.01 Da        Isoelectric Point: 4.3775

>AT182279 WP_102117299.1 NZ_CP065178:c3460695-3460468 [Pectobacterium quasiaquaticum]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIMLRPVKPNWQSFLQEDRADADFMTERQDVVEEGRFEL

Download         Length: 228 bp

>AT182279 NZ_CP086385:9175-9414 [Deinococcus radiophilus]
ATGACCACAGCCAAGATTTTCCAGACCGGCCGCTCGCAGGCCGTACGGCTTCCCAAGGCTTTCCGCTTCGAAGGGCAGGA
AGTCACTATTAAGCGGGTCTCTACTGGCGTGCTGCTGATTCCCAACACTCCAGGCAGCCATGAAGAGTTCTGGCAGGCGT
GGTATGCCGCGCTGCCTGAAGTGGACGTGCCCCTGACCCGTGAAGACCTGCCCCAGCAAGAACGGAACTGGGACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References